Phlebovirus-associated diseases transmitted by phlebotominae in Spain: Are we at risk?
Sign Up to like & getrecommendations! Published in 2021 at "Enfermedades infecciosas y microbiologia clinica"
DOI: 10.1016/j.eimce.2021.05.001
Abstract: The genera Phlebovirus transmitted by Diptera belonging to the Psychodidae family are a cause of self-limited febrile syndrome in the Mediterranean basin in summer and autumn. Toscana virus can also cause meningitis and meningoencephalitis. In… read more here.
Keywords: risk; phlebovirus associated; associated diseases; toscana virus ... See more keywords
Structure and function of the Toscana virus cap-snatching endonuclease
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz838
Abstract: Abstract Toscana virus (TOSV) is an arthropod-borne human pathogen responsible for seasonal outbreaks of fever and meningoencephalitis in the Mediterranean basin. TOSV is a segmented negative-strand RNA virus (sNSV) that belongs to the genus phlebovirus… read more here.
Keywords: structure; toscana virus; snatching endonuclease; cap snatching ... See more keywords
The initial detection of Toscana virus in phlebotomine sandflies from Turkey
Sign Up to like & getrecommendations! Published in 2020 at "Medical and Veterinary Entomology"
DOI: 10.1111/mve.12450
Abstract: Toscana virus (TOSV) is a prominent arthropod‐borne viral agent of human central nervous system infections occurring in the Mediterranean region. The main transmission route to susceptible individuals involves sandflies as vectors. Despite several reports revealing… read more here.
Keywords: initial detection; toscana virus; sandflies turkey; tosv ... See more keywords
Exposure to Phlebotomus perniciosus sandfly vectors is positively associated with Toscana virus and Leishmania infantum infection in human blood donors in Murcia Region, southeast Spain
Sign Up to like & getrecommendations! Published in 2022 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.14520
Abstract: Abstract Antibodies against Phlebotomus perniciosus sandfly salivary gland homogenate (SGH) and recombinant protein rSP03B, sandfly‐borne Toscana virus (TOSV), Sandfly Fever Sicilian virus (SFSV) and Leishmania, as well as DNA of the latter parasite, were investigated… read more here.
Keywords: toscana virus; perniciosus sandfly; sandfly; leishmania ... See more keywords
Toscana virus meningo-encephalitis: an important differential diagnosis for elderly travellers returning from Mediterranean countries
Sign Up to like & getrecommendations! Published in 2017 at "BMC Geriatrics"
DOI: 10.1186/s12877-017-0593-2
Abstract: BackgroundElderly patients have a long list of differentials for causes of acute confusion and altered consciousness levels, including infectious agents. In addition, elderly, retired patients often have more time to travel for tourism, particularly to… read more here.
Keywords: mediterranean countries; differential diagnosis; toscana virus; encephalitis ... See more keywords
Characterisation of the antiviral RNA interference response to Toscana virus in sand fly cells.
Sign Up to like & getrecommendations! Published in 2023 at "PLoS pathogens"
DOI: 10.1371/journal.ppat.1011283
Abstract: Toscana virus (TOSV) (Bunyavirales, Phenuiviridae, Phlebovirus, Toscana phlebovirus) and other related human pathogenic arboviruses are transmitted by phlebotomine sand flies. TOSV has been reported in nations bordering the Mediterranean Sea among other regions. Infection can… read more here.
Keywords: toscana virus; exo sirna; rna interference; sand ... See more keywords
Infectious Toscana Virus in Seminal Fluid of Young Man Returning from Elba Island, Italy
Sign Up to like & getrecommendations! Published in 2022 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2804.211920
Abstract: We report detecting infectious Toscana virus in the seminal fluid of a 25-year-old man from Italy returning from Elba Island. The presence of infectious virus in human semen adds Toscana virus to the long list… read more here.
Keywords: fluid; virus seminal; returning elba; toscana virus ... See more keywords
Novel Toscana Virus Reverse Genetics System Establishes NSs as an Antagonist of Type I Interferon Responses
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12040400
Abstract: The sand fly-borne Toscana virus (TOSV) is the major cause of human meningoencephalitis in the Mediterranean basin during the summer season. In this work, we have developed a T7 RNA polymerase-driven reverse genetics system to… read more here.
Keywords: reverse genetics; genetics; toscana virus; genetics system ... See more keywords
Ubiquitin and Not Only Unfolded Domains Drives Toscana Virus Non-Structural NSs Protein Degradation
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12101153
Abstract: The non-structural protein NSs of the Phenuiviridae family members appears to have a role in the host immunity escape. The stability of Toscana virus (TOSV) NSs protein was tested by a cycloheximide (CHX) chase approach… read more here.
Keywords: protein; tosv nss; nss protein; non structural ... See more keywords
Seroprevalence study of Toscana virus in Yafran area, Libya
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Vector Borne Diseases"
DOI: 10.4103/0972-9062.335728
Abstract: Background & objectives: In Mediterranean countries, infection of Toscana virus is a public health problem during the summer season, related to sandflies activity; it may cause aseptic meningitis and mild meningoencephalitis. We investigated the presence… read more here.
Keywords: yafran; toscana virus; area; seroprevalence study ... See more keywords