Total Syntheses of Basiliolide A1, Basiliolide A2, Basiliolide C, and their Structural Analogues
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701211
Abstract: A small focus library of basiliolides including basiliolide A₁, basiliolide A₂, basiliolide C and their structural analogues have been prepared for the structure-activity relationship study. The synthesis features a cyclopropanation/ring-opening strategy for establishing the C8… read more here.
Keywords: cyclopropanation; total syntheses; structural analogues; basiliolide structural ... See more keywords
Total syntheses of bupleurynol and its analog
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DOI: 10.1016/j.cclet.2016.11.032
Abstract: An efficient route to the natural products bupleurynol and its analog (RB-2), isolated from Bupleuri Radix, was established based on versatile intermediate (15). In this synthetic route, Sonogashira and Cadiot–Chodkiewicz coupling as well as Julia–Kocienski… read more here.
Keywords: total syntheses; syntheses bupleurynol; bupleurynol analog; route ... See more keywords
Asymmetric total syntheses of teretifolione B and methylteretifolione B via Diels-Alder reaction of optically active pyranobenzyne and substituted furans
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.06.050
Abstract: Abstract We report the asymmetric total syntheses of teretifolione B and methylteretifolione B, which are benzochromenes originally isolated from Conospermum plants. The synthesis involves enzymatic asymmetric transesterification of racemic acetoxychromene and construction of the basic… read more here.
Keywords: via diels; total syntheses; syntheses teretifolione; teretifolione methylteretifolione ... See more keywords
A convergent approach to batzelladine alkaloids. Total syntheses of (+)-batzelladine E, (-)-dehydrobatzelladine C, and (+)-batzelladine K.
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.04.050
Abstract: We recently reported a convergent strategy to access the polycyclic guanidinium alkaloid (+)-batzelladine B via an aldol addition-retro-aldol-aza-Michael addition cascade. Here we describe the application of this approach toward the total syntheses of (+)-batzelladine E,… read more here.
Keywords: total syntheses; batzelladine; syntheses batzelladine; dehydrobatzelladine batzelladine ... See more keywords
Total syntheses via cyclopropanols
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DOI: 10.1016/j.tet.2018.11.026
Abstract: Abstract Cyclopropanols are readily available via the Kulinkovich cyclopropanation, the Simmons-Smith reaction, and other synthetic methods. Due to their intrinsic ring stains, cyclopropanols and their derivatives are highly reactive and can be converted to different… read more here.
Keywords: total syntheses; syntheses via; via cyclopropanols;
Total syntheses of (+)- and (−)-Crinane via Pd(0)-Catalyzed deacylative allylation
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.131928
Abstract: Abstract An efficient Pd(0)-catalyzed deacylative allylation (DaA) of enolcarbonates (pro-nucleophile) prepared from 2-arylcyclohexanones sharing acyl functionality at C2-position with readily available allylic alcohols (pro-electrophiles) by employing Pd(0)-catalysis under mild reaction conditions. The methodology can be… read more here.
Keywords: syntheses crinane; methodology; catalyzed deacylative; total syntheses ... See more keywords
Recent total syntheses of anthraquinone-based natural products.
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DOI: 10.1016/j.tet.2021.132501
Abstract: The scientific community has found deep interest in anthraquinone-based compounds due to their therapeutic properties and challenging structural elements. Various architecturally beautiful natural products have been successfully synthesized in recent decades utilizing two main strategies:… read more here.
Keywords: syntheses anthraquinone; anthraquinone based; total syntheses; recent total ... See more keywords
Divergent total syntheses of pseudoberberine and nitidine through C H vinylation and switchable 6π electrocyclizations
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.152839
Abstract: Abstract Quaternary protoberberine alkaloids and quaternary benzophenanthridine alkaloids are two biosynthetically related natural product families of biological importance. Although significant advances have been achieved in the synthetic chemistry of these alkaloids, a unified approach to… read more here.
Keywords: divergent total; total syntheses; vinylation switchable; pseudoberberine nitidine ... See more keywords
The Journey of Schinortriterpenoid Total Syntheses.
Sign Up to like & getrecommendations! Published in 2019 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.8b00569
Abstract: Plants in the Schisandraceae family are important components of the traditional Chinese herbal medicines and are often used to treat various illnesses. Therefore, these Schisandraceae plants are valuable sources for the discovery of new chemical… read more here.
Keywords: total syntheses; schinortriterpenoid total; schisandraceae family; chemistry ... See more keywords
Cyclopropanation Strategies in Recent Total Syntheses.
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DOI: 10.1021/acs.chemrev.6b00798
Abstract: Complex molecular architectures containing cyclopropanes present significant challenges for any synthetic chemist. This review aims to highlight the strategic considerations for introduction of the cyclopropane motif in a collection of recent total syntheses. At first,… read more here.
Keywords: total syntheses; cyclopropanation strategies; recent total; strategies recent ... See more keywords
Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.
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DOI: 10.1021/acs.chemrev.6b00820
Abstract: A review of efforts that have provided total syntheses of vancomycin and related glycopeptide antibiotics, their agylcons, and key analogues is provided. It is a tribute to developments in organic chemistry and the field of… read more here.
Keywords: total syntheses; vancomycin related; key analogues; related glycopeptide ... See more keywords