Association of Nonconcussive Repetitive Head Impacts and Intense Physical Activity With Levels of Phosphorylated Tau181 and Total Tau in Plasma of Young Elite Soccer Players
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.6101
Abstract: Key Points Question What is the association of nonconcussive repetitive head impacts with plasma levels of phosphorylated and total tau proteins, and how might they be associated with cognitive outcomes in young elite soccer players?… read more here.
Keywords: head impacts; nonconcussive repetitive; repetitive head; elite soccer ... See more keywords
Assessment of Racial Disparities in Biomarkers for Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2018.4249
Abstract: Importance Racial differences in molecular biomarkers for Alzheimer disease may suggest race-dependent biological mechanisms. Objective To ascertain whether there are racial disparities in molecular biomarkers for Alzheimer disease. Design, Setting, and Participants A total of… read more here.
Keywords: alzheimer disease; total tau; disease; biomarkers alzheimer ... See more keywords
Plasma total‐tau as a biomarker of stroke risk in the community
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25542
Abstract: Higher plasma total‐tau level is associated with incident dementia, but its relationship with stroke risk is unknown. In this prospective community‐based study, we evaluated plasma total‐tau level as a biomarker of stroke risk in 2,794… read more here.
Keywords: plasma total; community; stroke risk; total tau ... See more keywords
Serum and saliva total tau protein as a marker for relapsing-remitting multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2019.109476
Abstract: Multiple sclerosis (MS) is considered as motor and sensory function loss, which results from demyelination and following axonal lesion. Tau protein interferes in the construction and stabilization of microtubules that are needed for axonal transport.… read more here.
Keywords: protein; saliva total; total tau; serum ... See more keywords
N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awab481
Abstract: Abstract Brain-derived tau secreted into CSF and blood consists of different N-terminal and mid-domain fragments, which may have a differential temporal course and thus, biomarker potential across the Alzheimer’s disease continuum or in other neurological… read more here.
Keywords: tau; alzheimer disease; tau biomarkers; neurological diseases ... See more keywords
Neurofilament light chain and total tau in the differential diagnosis and prognostic evaluation of acute and chronic inflammatory polyneuropathies
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15428
Abstract: To investigate the diagnostic and prognostic value of axonal injury biomarkers in patients with inflammatory polyneuropathies. read more here.
Keywords: tau differential; chain total; neurofilament light; inflammatory polyneuropathies ... See more keywords
Amyloid β42 and Total Tau Levels in Cerebrospinal Fluid Associate with Survival in an 85-Year-Old Population-Based Cohort Followed until Death
Sign Up to like & getrecommendations! Published in 2019 at "Dementia and Geriatric Cognitive Disorders"
DOI: 10.1159/000499066
Abstract: Background: Dementia of Alzheimer’s type (AD) is related to decreased survival. It is not clear whether also biological markers of AD are related to mortality. Low levels of amyloid beta-42 (Aβ42) and high levels of… read more here.
Keywords: death; dementia; total tau; csf ... See more keywords
Plasma Amyloid Beta, Total-Tau and Neurofilament Light Chain Levels and the Risk of Stroke: A Prospective Population-Based Study.
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200004
Abstract: BACKGROUND AND OBJECTIVES To unravel whether Alzheimer's disease-related pathology or neurodegeneration play a role in stroke etiology, we determined the effect of plasma levels amyloid β (Aβ), total-tau and neurofilament light chain (NfL) on risk… read more here.
Keywords: risk stroke; etiology; plasma; total tau ... See more keywords
Modulation of Amyloid-β and Tau in Alzheimer’s Disease Plasma Neuronal-Derived Extracellular Vesicles by Cerebrolysin® and Donepezil
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-220575
Abstract: Background: Plasma neuronal-derived extracellular vesicles (NDEV) contain proteins of pathological, diagnostic, and therapeutic relevance. Objective: We investigated the associations of six plasma NDEV markers with Alzheimer’s disease (AD) severity, cognition and functioning, and changes in… read more here.
Keywords: tau; cerebrolysin donepezil; alzheimer disease; plasma neuronal ... See more keywords
Cerebrospinal Fluid Total Tau Protein Correlates With Longitudinal, Progressing Cognitive Dysfunction in Anti-Neural Autoantibody-Associated Dementia and Alzheimer’s Dementia: A Case–Control Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.837376
Abstract: Background Neural autoantibody-associated dementia (NABD) is an increasing phenomenon in memory clinics with a high impact on later therapy. Biomarkers are lacking that differentiate this type of dementia from neurodegenerative dementia such as Alzheimer’s dementia… read more here.
Keywords: cognitive dysfunction; total tau; tau protein; dementia ... See more keywords
The Validation of Multifactor Model of Plasma Aβ42 and Total-Tau in Combination With MoCA for Diagnosing Probable Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00212
Abstract: Alzheimer disease (AD) has an insidious onset and heterogeneous clinical symptoms. The well-accepted biomarkers for clinical diagnosis of AD include β-amyloid (Aβ) deposition and pathologic tau level within cerebral spinal fluid (CSF) and imaging AD… read more here.
Keywords: plasma total; tau; alzheimer disease; total tau ... See more keywords