Synthesis and antiproliferative activity of podocarpane and totarane derivatives.
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DOI: 10.1016/j.ejmech.2018.09.051
Abstract: The synthesis of podocarpanes, including 12,19-dihydroxy-13-acetyl-8,11,13-podocarpatriene (23), isolated from Gaultheria yunnanensis and not previously synthesized, and totarane-type terpenoids, starting from the natural labdane trans-communic acid (15), is described. Their antiproliferative activities against MCF-7, T-84 and… read more here.
Keywords: podocarpane totarane; activity podocarpane; synthesis antiproliferative; antiproliferative activity ... See more keywords