Safety and Efficacy of Flexible-Dose Deutetrabenazine in Children and Adolescents With Tourette Syndrome: A Randomized Clinical Trial.
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DOI: 10.1001/jamanetworkopen.2021.28204
Abstract: Importance Tourette syndrome is a neurodevelopmental disorder characterized by childhood onset of motor and phonic tics; treatments for tics are associated with safety concerns. Deutetrabenazine is a selective vesicular monoamine transporter 2 inhibitor approved for… read more here.
Keywords: trial; safety; children adolescents; deutetrabenazine ... See more keywords
Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents With Tourette Syndrome
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DOI: 10.1001/jamanetworkopen.2022.25614
Abstract: Key Points Question Is therapist-supported, internet-delivered exposure and response prevention (ERP) efficacious and cost-effective for young people with Tourette syndrome or chronic tic disorder? Findings In this randomized clinical trial of 221 youths with Tourette… read more here.
Keywords: therapist supported; internet delivered; internet; supported internet ... See more keywords
Association of Tourette Syndrome and Chronic Tic Disorder With Metabolic and Cardiovascular Disorders
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DOI: 10.1001/jamaneurol.2018.4279
Abstract: Importance There are limited data concerning the risk of metabolic and cardiovascular disorders among individuals with Tourette syndrome (TS) or chronic tic disorder (CTD). Objective To investigate the risk of metabolic and cardiovascular disorders among… read more here.
Keywords: disorder; risk metabolic; metabolic cardiovascular; cardiovascular disorders ... See more keywords
Association of Tourette Syndrome and Chronic Tic Disorder With Violent Assault and Criminal Convictions
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DOI: 10.1001/jamaneurol.2022.0167
Abstract: This cohort study investigates whether Tourette syndrome or chronic tic disorder are associated with an increased risk of experiencing violent assault and criminal convictions. read more here.
Keywords: syndrome chronic; assault criminal; chronic tic; tic disorder ... See more keywords
Pallidal and thalamic neural oscillatory patterns in tourette's syndrome
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DOI: 10.1002/ana.25311
Abstract: Aberrant oscillatory activity has been hypothesized to play a role in the pathophysiology of Tourette's syndrome (TS). Deep brain stimulation (DBS) has recently been established as an effective treatment for severe TS. Modulation of symptom‐specific… read more here.
Keywords: thalamic neural; neural oscillatory; pallidal thalamic; oscillatory patterns ... See more keywords
Deep brain stimulation modulates pallidal and subthalamic neural oscillations in Tourette's syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1450
Abstract: Previous studies found subthalamic nucleus deep brain stimulation (STN‐DBS) has clinical effect on Parkinson's disease, dystonia, and obsessive compulsive disorder. It is noteworthy that only a few studies report the STN‐DBS for Tourette's syndrome (TS).… read more here.
Keywords: deep brain; neural oscillations; brain; tourette syndrome ... See more keywords
Role of histidine decarboxylase gene in the pathogenesis of Tourette syndrome
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DOI: 10.1002/brb3.2511
Abstract: Tourette syndrome (TS) is caused by complex genetic and environmental factors and is characterized by tics. Histidine decarboxylase (HDC) mutation is a rare genetic cause with high penetrance in patients with TS. HDC‐knockout (KO) mice… read more here.
Keywords: tourette syndrome; role histidine; decarboxylase gene; histidine decarboxylase ... See more keywords
ASH1L may contribute to the risk of Tourette syndrome: Combination of family‐based analysis and case–control study
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DOI: 10.1002/brb3.2539
Abstract: Tourette syndrome (TS) is a childhood neurodevelopmental disorder caused by various genetic and environmental factors and presents with apparent genetic heterogeneity. As ASH1L potentially contributes to neurodevelopmental diseases, especially in TS, we aim to investigate… read more here.
Keywords: tourette; may contribute; contribute risk; ash1l may ... See more keywords
Gastrodin attenuates neuroinflammation in DOI‐induce Tourette syndrome in rats
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DOI: 10.1002/jbt.22302
Abstract: Tourette syndrome (TS) is a chronic neuropsychiatric disorder. Its clinical manifestations are involuntary and recurrent muscle twitch, resulting in motor twitch and occurrence twitch. Traditional Chinese medicine has obvious advantages in treating TS. The aim… read more here.
Keywords: attenuates neuroinflammation; gastrodin attenuates; tourette; doi ... See more keywords
Gastrodin alleviates Tourette syndrome via Nrf‐2/HO‐1/HMGB1/NF‐кB pathway
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DOI: 10.1002/jbt.22389
Abstract: The aim is to study the effects of gastrodin (GA) on striatal inflammation and oxidative stress in rats with Tourette syndrome (TS). The rat model of TS was induced by 3,3′‐iminodipropionitrile. Behavioral tests were carried… read more here.
Keywords: nrf hmgb1; hmgb1 pathway; striatum; group ... See more keywords
Tourette Syndrome and Driving
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DOI: 10.1002/mdc3.13225
Abstract: Driving ability may be impaired in patients with various movement disorders, but it has not been studied in patients with Tourette syndrome (TS). read more here.
Keywords: syndrome driving; tourette syndrome;