Abstract 3414: The pan-RAF inhibitor tovorafenib suppresses NF1-mutant glioma through upregulation of FOXO1 and triggering of oncogene-induced senescence
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DOI: 10.1158/1538-7445.am2023-3414
Abstract: Pediatric low-grade glioma (pLGG) is the most common childhood brain tumor. Patients with pLGG often have significant lifelong disabilities due to the location of the tumor and tumor treatments, including surgery, chemotherapy, and radiation. The… read more here.
Keywords: mutant glioma; tovorafenib; senescence; foxo1 ... See more keywords