Toward effective Atg8-based ATTECs: Approaches and perspectives.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30380
Abstract: Induction of Atg8-family protein (LC3/GABARAP proteins in human) interactions with target proteins of interest by proximity-inducing small molecules offers the possibility for novel targeted protein degradation approaches. However, despite intensive screening campaigns during the last 5… read more here.
Keywords: lc3 gabarap; toward effective; effective atg8; atg8 based ... See more keywords
Toward Effective Detection of the Bifurcation Locus of Real Polynomial Maps
Sign Up to like & getrecommendations! Published in 2017 at "Foundations of Computational Mathematics"
DOI: 10.1007/s10208-016-9303-2
Abstract: We answer to a problem raised by recent work of Jelonek and Kurdyka: how can one detect by rational arcs the bifurcation locus of a polynomial map $${\mathbb {R}}^n\rightarrow {\mathbb {R}}^p$$Rn→Rp in case $$p>1$$p>1. We… read more here.
Keywords: effective detection; bifurcation locus; toward effective; detection bifurcation ... See more keywords
Re-purposing CORDIAL? Toward an effective treatment for depression in dementia
Sign Up to like & getrecommendations! Published in 2021 at "International Psychogeriatrics"
DOI: 10.1017/s1041610220001209
Abstract: High-quality, rigorous, large-scale evaluations of psychosocial interventions in dementia care always represent a valuable addition to the literature. It is good, then, to see a randomized controlled trial of the CORDIAL program, originally developed in… read more here.
Keywords: cordial toward; cordial program; purposing cordial; toward effective ... See more keywords
Toward an Effective Control of the H2 to CO Ratio of Syngas through CO2 Electroreduction over Immobilized Gold Nanoparticles on Layered Titanate Nanosheets
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b00647
Abstract: In recent years, the electroreduction of CO2 to valuable products has emerged as a rational answer to rising CO2 emissions and a strategic approach to incorporate renewable electricity from intermittent sources (e.g., wind and solar)… read more here.
Keywords: gold nanoparticles; toward effective; co2; syngas ... See more keywords
TADDOL-Derived Cationic Phosphonites: Toward an Effective Enantioselective Synthesis of [6]Helicenes via Au-Catalyzed Alkyne Hydroarylation
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b01374
Abstract: A series of cationic phosphonites, all sharing a TADDOL skeleton but decorated with different positively charged substituents at phosphorus, were synthesized and tested as chiral ancillary ligands on the Au-catalyzed intramolecular hydroarylation of appropriate diynes… read more here.
Keywords: hydroarylation; derived cationic; toward effective; taddol derived ... See more keywords
Toward More Effective Legal Education for Adolescents: Systematic or Constructivist Instructional Design Models?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Constructivist Psychology"
DOI: 10.1080/10720537.2019.1641773
Abstract: The present article aimed to compare the effectiveness of two approaches—systematic and constructivist instructional design models—in communicating legal knowledge to students. Three instructional models have been tried in this investigation. Both of them were designed… read more here.
Keywords: instructional design; toward effective; constructivist instructional; systematic constructivist ... See more keywords
Needs and pathways for strengthening the contribution of qualitative methods toward more effective impact assessment practice
Sign Up to like & getrecommendations! Published in 2025 at "Impact Assessment and Project Appraisal"
DOI: 10.1080/14615517.2025.2515776
Abstract: ABSTRACT Many jurisdictions are looking to next-generation impact assessment (IA) that includes sustainability considerations that extend beyond biophysical. Subjectivity is inherent in many of these additional impact considerations, and they are often not easily nor… read more here.
Keywords: toward effective; practice; impact assessment; impact ... See more keywords
Ubermag: Toward More Effective Micromagnetic Workflows
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Magnetics"
DOI: 10.1109/tmag.2021.3078896
Abstract: Computational micromagnetics has become an essential tool in academia and industry to support fundamental research and the design and development of devices. Consequently, computational micromagnetics is widely used in the community, and the fraction of… read more here.
Keywords: effective micromagnetic; toward effective; micromagnetic workflows; environment ... See more keywords
Toward Effective AI Support for Developers
Sign Up to like & getrecommendations! Published in 2024 at "Communications of the ACM"
DOI: 10.1145/3690928
Abstract: The journey of integrating AI into the daily lives of software engineers is not without its challenges. Yet, it promises a transformative shift in how developers can translate their creative visions into tangible solutions. As… read more here.
Keywords: support developers; toward effective; effective support;
Toward More Effective Tiered Systems: Lessons From National Implementation Efforts
Sign Up to like & getrecommendations! Published in 2017 at "Exceptional Children"
DOI: 10.1177/0014402917693565
Abstract: Based on the 2015 evaluation of response-to-intervention (RTI) efforts and our own 2 decades of experience in supporting educators’ implementation of RTI efforts, four recommendations are presented to advance effective implementation of tiered systems of… read more here.
Keywords: systems lessons; lessons national; tiered systems; implementation ... See more keywords
Toward Effective Vaccines Against Piscine Orthoreovirus: Challenges and Current Strategies
Sign Up to like & getrecommendations! Published in 2025 at "Viruses"
DOI: 10.3390/v17101372
Abstract: Piscine orthoreovirus (PRV) is a globally distributed viral pathogen that causes heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar) and affects other salmonids, yet no commercial vaccines are currently available. Major barriers… read more here.
Keywords: toward effective; challenges current; effective vaccines; vaccines piscine ... See more keywords