Understanding Mutational Drivers of Risk: An Important Step Toward Personalized Care for Patients with Renal Cell Carcinoma.
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DOI: 10.1016/j.euf.2016.07.008
Abstract: The identification of clinically relevant genetic mutations in renal cell carcinoma is an important step on the path toward personalized management of this disease. read more here.
Keywords: cell carcinoma; renal cell; toward personalized; important step ... See more keywords
First Steps toward Personalized Therapies for ABCA3 Deficiency
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DOI: 10.1165/rcmb.2021-0405ed
Abstract: The ABCA3 (ATP-binding cassette transporter A3) protein transports phospholipids from the cytoplasm into lamellar bodies in alveolar type II cells (AEC2s) and is critical for pulmonary surfactant synthesis and function. Biallelic pathogenic ABCA3 variants cause… read more here.
Keywords: first steps; steps toward; therapies abca3; toward personalized ... See more keywords
Omalizumab for severe asthma: toward personalized treatment based on biomarker profile and clinical history
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DOI: 10.2147/jaa.s107982
Abstract: Asthma is a heterogeneous syndrome with numerous underlining molecular and inflammatory mechanisms contributing to the wide spectrum of clinical phenotypes. Multiple therapies targeting severe asthma with type 2 (T2) high inflammation are or soon will… read more here.
Keywords: clinical history; omalizumab severe; severe asthma; asthma toward ... See more keywords