A gold(i)-catalysed approach towards harmalidine an elusive alkaloid from Peganum harmala
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DOI: 10.1039/d2ra05685b
Abstract: Upon gold catalysis, the 2,3-dihydropyrrolo[1,2-a]indole motif, encountered in few but interesting bioactive natural products, was efficiently obtained from N-aryl 2-alkynylazetidine derivatives. In an attempt to apply this methodology to the synthesis of harmalidine, isolated from… read more here.
Keywords: harmala; approach towards; peganum harmala; towards harmalidine ... See more keywords