Moving towards a novel therapeutic strategy for hyperammonemia that targets glutamine metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12540
Abstract: Patients with urea cycle disorders intermittently develop episodes of decompensation with hyperammonemia. Although such an episode is often associated with starvation and catabolism, its molecular basis is not fully understood. First, we attempted to elucidate… read more here.
Keywords: moving towards; novel therapeutic; therapeutic strategy; starvation ... See more keywords
Towards a novel therapy against AIDS.
Sign Up to like & getrecommendations! Published in 2020 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2020.109569
Abstract: AIDS is an infectious disease that kills over a million people per year. Very recently, Dash et al have for the first time reached the functional cure in HIV-infected humanized mice using CRISPR-Cas9 in combination… read more here.
Keywords: therapy aids; novel therapy; towards novel;
Electronic properties of graphene oxide: nanoroads towards novel applications.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00251e
Abstract: In this work, we suggest an approach to manipulate the electronic properties of graphene oxide in a controllable manner. We study graphene nanoroads paved inside graphene oxide using density functional calculations. We show that this… read more here.
Keywords: oxide nanoroads; towards novel; nanoroads towards; properties graphene ... See more keywords
Towards Novel Non-Invasive Colorectal Cancer Screening Methods: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13081820
Abstract: Simple Summary Since the 70s, a variety of colorectal cancer (CRC) screening programs have been adopted throughout the world with the aim of reducing the mortality rate of one of the leading cancer-related causes of… read more here.
Keywords: colorectal cancer; review; towards novel; cancer ... See more keywords
Routes towards Novel Collagen-Like Biomaterials
Sign Up to like & getrecommendations! Published in 2018 at "Fibers"
DOI: 10.3390/fib6020021
Abstract: Collagen plays a major role in providing mechanical support within the extracellular matrix and thus has long been used for various biomedical purposes. Exemplary, it is able to replace damaged tissues without causing adverse reactions… read more here.
Keywords: collagen; collagen like; novel collagen; like biomaterials ... See more keywords
Towards Novel Potential Molecular Targets for Antidepressant and Antipsychotic Pharmacotherapies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119482
Abstract: Depression and schizophrenia are two highly prevalent and severely debilitating neuropsychiatric disorders. Both conventional antidepressant and antipsychotic pharmacotherapies are often inefficient clinically, causing multiple side effects and serious patient compliance problems. Collectively, this calls for… read more here.
Keywords: potential molecular; antidepressant antipsychotic; molecular targets; antipsychotic pharmacotherapies ... See more keywords