Cationic polysaccharide spermine-pullulan drives tumor associated macrophage towards M1 phenotype to inhibit tumor progression.
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DOI: 10.1016/j.ijbiomac.2018.11.089
Abstract: Macrophages are predominant immune cells in the tumor microenvironment where they display an immunosuppressive M2 phenotype to support tumor growth. Reprogramming M2-like tumor-associated macrophages (TAMs) to antitumor M1 phenotype represents as a promising strategy in… read more here.
Keywords: tumor progression; towards phenotype; tumor associated; polysaccharide spermine ... See more keywords