Towards a Rational Design of Macrolide Antibiotics in Order to Combat Bacterial Resistance
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DOI: 10.1016/j.bpj.2016.11.1749
Abstract: Macrolides, which bind in the protein exit tunnel of the bacterial ribosome, are one of the most prescribed classes of antibiotics.However, macrolide resistance caused by ribosomal modifications at base A2058 in segment 23S is a… read more here.
Keywords: macrolide; bacterial resistance; towards rational; resistance ... See more keywords