Towards the synthesis of prenylated phloroglucinol derivatives: An X-ray crystallographic and DFT study of unexpected reaction products
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.03.097
Abstract: Abstract Owing to their bioactivity and prevalence in medicinal plant extracts, prenylated phloroglucinols have garnered significant interest. Towards the synthesis of prenylated phloroglucinol derivatives, 2,4,6-trihydroxy-3-(3-methylbut-2-enyl)acetophenone is required as an intermediate. Herein, this was synthesised by… read more here.
Keywords: hydrogen bonded; dft; hydrogen; towards synthesis ... See more keywords
Studies towards the synthesis of ertugliflozin from l-Arabinose
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.08.005
Abstract: Abstract A new method for the diastereoselective synthesis of enantiomerically pure ertugliflozin was developed. The crucial step involves an aldol condensation between 1-(4-chloro-3-(4-ethoxybenzyl)phenyl)ethanone and (4R,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-5-((trityloxy)methyl)-1,3-dioxolane-4-carbaldehyde, which was prepared from known 2-C-trityloxymethyl-2,3-O-isopropylidene- l -erythrose (easily accessible… read more here.
Keywords: ertugliflozin arabinose; towards synthesis; studies towards; ertugliflozin ... See more keywords
Copper promoted desulfurization towards the synthesis of isothiocyanates
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DOI: 10.1016/j.tetlet.2016.11.086
Abstract: Abstract The cheap, readily available and air stable catalyst was used as the desulfurization agent for the conversion of aniline to isothiocyanates in one pot two step reaction under mild reaction conditions. read more here.
Keywords: promoted desulfurization; desulfurization; copper promoted; synthesis isothiocyanates ... See more keywords
Studies Directed towards the Synthesis of the Acridone Family of Natural Products: Total Synthesis of Acronycines and Atalaphyllidines
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DOI: 10.1021/acsomega.1c03629
Abstract: A modular and flexible three-step synthetic strategy has been developed for the synthesis of acridone natural products of biological significance. The tetracyclic core of acridone derivatives has been achieved efficiently in high yield from commercially… read more here.
Keywords: natural products; directed towards; towards synthesis; studies directed ... See more keywords
An Expeditious Approach towards the Synthesis and Application of Water-Soluble and Photostable Fluorogenic Chromones for DNA Detection
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072267
Abstract: The intensive research for hybridization probes based on organic molecules with fluorogenic properties is currently attracting particular attention due to their potential to efficiently recognize different DNA conformations and the local environment. However, most established… read more here.
Keywords: dna; approach towards; water; synthesis application ... See more keywords