Aldehyde dehydrogenase 2 activation ameliorates cyclophosphamide-induced acute cardiotoxicity via detoxification of toxic aldehydes and suppression of cardiac cell death.
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DOI: 10.1016/j.yjmcc.2018.07.006
Abstract: Cyclophosphamide (CY)-induced acute cardiotoxicity is a common side effect which is dose dependent. It is reported that up to 20% of patients received high dose of CY treatment suffered from acute cardiac dysfunction. However, the… read more here.
Keywords: cell death; toxic aldehydes; induced acute; acute cardiotoxicity ... See more keywords