Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells
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DOI: 10.15252/embr.201745336
Abstract: Trinucleotide repeat (TNR) expansions in the genome cause a number of degenerative diseases. A prominent TNR expansion involves the triplet CAG in the huntingtin (HTT) gene responsible for Huntington's disease (HD). Pathology is caused by… read more here.
Keywords: toxic cancer; rnas based; small interfering; cancer cells ... See more keywords