Photodistributed Toxic Epidermal Necrolysis: Case Report and Review of Current Literature.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.1090
Abstract: Importance Cases of photodistributed Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have been infrequently reported since the first documented case in 1989. This emerging clinical entity and its underlying mechanism have yet to be… read more here.
Keywords: toxic epidermal; report; case report; case ... See more keywords
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures
Sign Up to like & getrecommendations! Published in 2017 at "Advances in Therapy"
DOI: 10.1007/s12325-017-0530-y
Abstract: IntroductionStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN.PurposeThe scientific… read more here.
Keywords: sjs ten; johnson syndrome; epidermal necrolysis; care ... See more keywords
Stevens-Johnson syndrome and toxic epidermal necrolysis in pregnant patients: A systematic review
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Women's Dermatology"
DOI: 10.1016/j.ijwd.2020.04.002
Abstract: Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic emergencies. Although pregnant women comprise a subset of individuals at risk for SJS and TEN development, little is known… read more here.
Keywords: epidermal necrolysis; pregnant patients; toxic epidermal; stevens johnson ... See more keywords
Vulvovaginal Manifestations in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Prevention and Treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.08.031
Abstract: The prevalence of acute vulvovaginal involvement in toxic epidermal necrolysis may be as high as 70%; up to 28% of females will also develop chronic vulvovaginal sequelae. There is little consensus regarding prevention and treatment… read more here.
Keywords: toxic epidermal; prevention treatment; epidermal necrolysis;
Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immunocell activation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.06.043
Abstract: Abstract Background Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied. Objective To summarize clinical characteristics of SJS/TEN-associated acute pancreatic… read more here.
Keywords: sjs ten; pancreatic injuries; johnson syndrome; epidermal necrolysis ... See more keywords
Performance of ABCD-10 and SCORTEN Mortality Prediction Models in a Cohort of Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2021.04.082
Abstract: BACKGROUND ABCD-10 has recently been proposed as an alternative to the SCORTEN model for predicting in-hospital mortality in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. In contrast to SCORTEN, ABCD-10 incorporates prior dialysis and… read more here.
Keywords: abcd; johnson syndrome; mortality; syndrome toxic ... See more keywords
Inhibition of tumor necrosis factor improves conventional steroid therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2022.01.039
Abstract: BACKGROUND Systemic steroid therapies for Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have been challenged due to their limited benefits. Whether additional tumor necrosis factor (TNF)-α inhibition provides an optimized approach remains unexplored. OBJECTIVE To investigate… read more here.
Keywords: epidermal necrolysis; johnson syndrome; inhibition; therapy ... See more keywords
Successful dabrafenib transition after vemurafenib-induced toxic epidermal necrolysis in a patient with metastatic melanoma
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DOI: 10.1016/j.jdcr.2018.08.003
Abstract: Vemurafenib improves survival in advanced metastatic melanoma, but has rarely been associated with severe skin reactions including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).1, 2 Dabrafenib is a BRAF inhibitor that shares a sulfonamide… read more here.
Keywords: vemurafenib induced; metastatic melanoma; epidermal necrolysis; toxic epidermal ... See more keywords
Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis
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DOI: 10.1038/s41467-024-52990-3
Abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen (HLA) class I-restricted CD8+ T cells. For unbiased assessment of cellular immunopathogenesis, here we perform… read more here.
Keywords: johnson syndrome; syndrome toxic; stevens johnson; cell ... See more keywords
Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2020.1740591
Abstract: ABSTRACT Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable with different severity. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse reactions (SCARs) majorly caused by drugs and… read more here.
Keywords: epidermal necrolysis; johnson syndrome; risk factors; stevens johnson ... See more keywords
Toxic Epidermal Necrolysis and Steven-Johnson Syndrome: A Comprehensive Review.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in wound care"
DOI: 10.1089/wound.2019.0977
Abstract: Significance: Toxic epidermal necrolysis (TEN) and Steven-Johnson syndrome (SJS) are potentially fatal acute mucocutaneous vesiculobullous disorders. Evidence to date suggests that outcomes for patients with both TEN and SJS are largely dependent on stopping the… read more here.
Keywords: steven johnson; johnson syndrome; toxic epidermal; epidermal necrolysis ... See more keywords