Articles with "toxic impurity" as a keyword



Advanced spectrophotometric resolution techniques for spectrally overlapping spasmolytic binary mixture along with Dichloroaniline as a toxic impurity: Application to content uniformity testing.

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Published in 2022 at "Journal of AOAC International"

DOI: 10.1093/jaoacint/qsac092

Abstract: BACKGROUND Irritable bowel syndrome (IBS) is considered an anxious disease leading to undesirable pain. Phloroglucinol (PHG) and Trimethylphloroglucinol (TMG) are co-formulated as spasmolytic medication that is considered to be effective in reducing smooth muscle spasm.… read more here.

Keywords: phg; tmg; phg tmg; dcl ... See more keywords
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A Comparative Chemometric Study for Quantitative Determination of Duloxetine Hydrochloride in the Presence of its Toxic Impurity 1-Naphthol

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Published in 2020 at "Current Pharmaceutical Analysis"

DOI: 10.2174/1573412915666190709093612

Abstract: Duloxetine hydrochloride (DUL) is a serotonin-norepinephrine reuptake inhibitor. It is used for treating depression and anxiety. It is available in the market as a capsule called Cymbatex®, which is used for the treatment of depression.… read more here.

Keywords: presence; toxic impurity; impurity naphthol; duloxetine hydrochloride ... See more keywords