AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00713-1
Abstract: Aflatoxin exposure is a crucial factor in promoting the development of primary hepatocellular carcinoma (HCC) in individuals infected with the hepatitis virus. However, the molecular pathways leading to its bioactivation and subsequent toxicity in hepatocytes… read more here.
Keywords: hepatocellular carcinoma; ahr mediates; ahr; toxicity ... See more keywords
Assessment of Drugs Toxicity and Associated Biomarker Genes Using Hierarchical Clustering
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DOI: 10.3390/medicina55080451
Abstract: Background and objectives: Assessment of drugs toxicity and associated biomarker genes is one of the most important tasks in the pre-clinical phase of drug development pipeline as well as in toxicogenomic studies. There are few… read more here.
Keywords: associated biomarker; biomarker; biomarker genes; assessment drugs ... See more keywords
Silymarin Encapsulated Liposomal Formulation: An Effective Treatment Modality against Copper Toxicity Associated Liver Dysfunction and Neurobehavioral Abnormalities in Wistar Rats
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DOI: 10.3390/molecules28031514
Abstract: Wilson’s disease causes copper accumulation in the liver and extrahepatic organs. The available therapies aim to lower copper levels by various means. However, a potent drug that can repair the damaged liver and brain tissue… read more here.
Keywords: toxicity associated; silymarin encapsulated; associated liver; toxicity ... See more keywords