Articles with "toxicity evaluation" as a keyword



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Toxicity Evaluation of Household Detergents and Surfactants Using Zebrafish

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Published in 2020 at "Biotechnology and Bioprocess Engineering"

DOI: 10.1007/s12257-020-0109-3

Abstract: There are concerns regarding the toxicity of household detergents to humans and aquatic organisms. There are various types of surfactants, which are the main components of detergents, and each detergent product has a different formulation.… read more here.

Keywords: household detergents; toxicity evaluation; detergents surfactants; toxicity ... See more keywords
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Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex

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Published in 2018 at "Asian Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ajps.2017.11.001

Abstract: Graphical Abstract For improving the utilization of NK, a complex of NK-TUDCA to reduce the toxicity of intravenous NK injection, was designed by using NK as the cationic moiety and TUDCA as the anionic moiety.… read more here.

Keywords: evaluation novel; toxicity evaluation; nattokinase tauroursodeoxycholate; novel nattokinase ... See more keywords
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Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells.

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Published in 2021 at "Journal of hazardous materials"

DOI: 10.1016/j.jhazmat.2021.126092

Abstract: There is a growing concern regarding the toxic effects of nanoplastics (NPs) on aquatic and marine organism, while relatively few studies about their toxicity evaluation on mammals are conducted. In the present study, we observed… read more here.

Keywords: toxicity evaluation; caco cells; polystyrene; caco ... See more keywords

Toxicity evaluation of two polyoxotungstates with anti‐acetylcholinesterase activity

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Published in 2017 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2017.08.010

Abstract: ABSTRACT A toxicity evaluation of two Keggin‐type heteropolytungstates, K7[Ti2PW10O40]·6H2O and K6H[SiV3W9O40]·3H2O, with different inhibitory potencies toward acetylcholinesterase activity (IC50 values of 1.04 × 10− 6 and 4.80 × 10− 4 mol/L, respectively) was performed. Wistar… read more here.

Keywords: two polyoxotungstates; evaluation two; toxicity evaluation; acetylcholinesterase ... See more keywords
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Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

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Published in 2021 at "Toxicology Reports"

DOI: 10.1016/j.toxrep.2021.07.022

Abstract: Highlights • Novel ceramide drug for breast cancer.• Toxicological profile was studied.• Single dose of 80 mg/kg dose was safe.• Single dose of 120 mg/kg caused minor liver and cardiac tissue damage. read more here.

Keywords: acute toxicity; novel ceramide; toxicity evaluation; breast cancer ... See more keywords

In vivo toxicity evaluation of nanoemulsions for drug delivery

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Published in 2019 at "Drug and Chemical Toxicology"

DOI: 10.1080/01480545.2019.1659806

Abstract: Abstract Lipid nanocarriers (LNs), for example nanoemulsions (NE), are an emerging tool for drug delivery due to their ability to incorporate drugs, protect the drug from degradation, improve bioavailability, and control release. Although LNs are… read more here.

Keywords: toxicity evaluation; drug delivery; delivery; drug ... See more keywords

Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract.

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Published in 2021 at "Drug and chemical toxicology"

DOI: 10.1080/01480545.2021.1883645

Abstract: Forsythia suspensa leaves (FSL), rich in phillyrin, forsythiaside A, phillygenin, rutin, and other compounds, is a known traditional Chinese medicine (TCM). It has been effective in heat retreat and detoxification. In this study, we performed… read more here.

Keywords: toxicity evaluation; suspensa leaves; toxicity; teratogenic toxicity ... See more keywords
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Biodistribution, pharmacokinetics and toxicity evaluation of mannosylated gelatin nanoparticles of linezolid for anti-tubercular therapy

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Published in 2020 at "Materials Technology"

DOI: 10.1080/10667857.2020.1816021

Abstract: The present study explores the therapeutic potential of gelatin nanoparticles as a carrier for the delivery of linezolid, a repurposed drug for the treatment of Mycobactrium tuberculosis. However, ... read more here.

Keywords: biodistribution pharmacokinetics; toxicity evaluation; mannosylated gelatin; pharmacokinetics toxicity ... See more keywords

Automatic Toxicity Evaluation for Human-LLM Conversations in Flexible Manufacturing System With Duplex Fine-Tuned LLMs

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Published in 2025 at "IEEE Internet of Things Journal"

DOI: 10.1109/jiot.2025.3592453

Abstract: Flexible manufacturing systems (FMS), empowered by the Industrial Internet of Things (IIoT), have become a cornerstone of Industry 6.0 by enabling dynamic production adaptation, real-time equipment monitoring, and intelligent scheduling. As these systems increasingly incorporate… read more here.

Keywords: toxicity evaluation; flexible manufacturing; human llm;

Preliminary Toxicity Evaluation of a Porphyrin Photosensitizer in an Alternative Preclinical Model

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043131

Abstract: In photodynamic therapy (PDT), a photosensitizer (PS) excited with a specific wavelength, and in the presence of oxygen, gives rise to photochemical reactions that lead to cell damage. Over the past few years, larval stages… read more here.

Keywords: evaluation porphyrin; toxicity; preliminary toxicity; model ... See more keywords

In Vitro Systems for Toxicity Evaluation of Microbial Volatile Organic Compounds on Humans: Current Status and Trends.

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Published in 2022 at "Journal of fungi"

DOI: 10.3390/jof8010075

Abstract: Microbial volatile organic compounds (mVOC) are metabolic products and by-products of bacteria and fungi. They play an important role in the biosphere: They are responsible for inter- and intra-species communication and can positively or negatively… read more here.

Keywords: vitro systems; organic compounds; systems toxicity; volatile organic ... See more keywords