Toxicity Evaluation of Household Detergents and Surfactants Using Zebrafish
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-020-0109-3
Abstract: There are concerns regarding the toxicity of household detergents to humans and aquatic organisms. There are various types of surfactants, which are the main components of detergents, and each detergent product has a different formulation.… read more here.
Keywords: household detergents; toxicity evaluation; detergents surfactants; toxicity ... See more keywords
Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2017.11.001
Abstract: Graphical Abstract For improving the utilization of NK, a complex of NK-TUDCA to reduce the toxicity of intravenous NK injection, was designed by using NK as the cationic moiety and TUDCA as the anionic moiety.… read more here.
Keywords: evaluation novel; toxicity evaluation; nattokinase tauroursodeoxycholate; novel nattokinase ... See more keywords
Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.126092
Abstract: There is a growing concern regarding the toxic effects of nanoplastics (NPs) on aquatic and marine organism, while relatively few studies about their toxicity evaluation on mammals are conducted. In the present study, we observed… read more here.
Keywords: toxicity evaluation; caco cells; polystyrene; caco ... See more keywords
Toxicity evaluation of two polyoxotungstates with anti‐acetylcholinesterase activity
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.08.010
Abstract: ABSTRACT A toxicity evaluation of two Keggin‐type heteropolytungstates, K7[Ti2PW10O40]·6H2O and K6H[SiV3W9O40]·3H2O, with different inhibitory potencies toward acetylcholinesterase activity (IC50 values of 1.04 × 10− 6 and 4.80 × 10− 4 mol/L, respectively) was performed. Wistar… read more here.
Keywords: two polyoxotungstates; evaluation two; toxicity evaluation; acetylcholinesterase ... See more keywords
Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology Reports"
DOI: 10.1016/j.toxrep.2021.07.022
Abstract: Highlights • Novel ceramide drug for breast cancer.• Toxicological profile was studied.• Single dose of 80 mg/kg dose was safe.• Single dose of 120 mg/kg caused minor liver and cardiac tissue damage. read more here.
Keywords: acute toxicity; novel ceramide; toxicity evaluation; breast cancer ... See more keywords
In vivo toxicity evaluation of nanoemulsions for drug delivery
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2019.1659806
Abstract: Abstract Lipid nanocarriers (LNs), for example nanoemulsions (NE), are an emerging tool for drug delivery due to their ability to incorporate drugs, protect the drug from degradation, improve bioavailability, and control release. Although LNs are… read more here.
Keywords: toxicity evaluation; drug delivery; delivery; drug ... See more keywords
Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract.
Sign Up to like & getrecommendations! Published in 2021 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2021.1883645
Abstract: Forsythia suspensa leaves (FSL), rich in phillyrin, forsythiaside A, phillygenin, rutin, and other compounds, is a known traditional Chinese medicine (TCM). It has been effective in heat retreat and detoxification. In this study, we performed… read more here.
Keywords: toxicity evaluation; suspensa leaves; toxicity; teratogenic toxicity ... See more keywords
Biodistribution, pharmacokinetics and toxicity evaluation of mannosylated gelatin nanoparticles of linezolid for anti-tubercular therapy
Sign Up to like & getrecommendations! Published in 2020 at "Materials Technology"
DOI: 10.1080/10667857.2020.1816021
Abstract: The present study explores the therapeutic potential of gelatin nanoparticles as a carrier for the delivery of linezolid, a repurposed drug for the treatment of Mycobactrium tuberculosis. However, ... read more here.
Keywords: biodistribution pharmacokinetics; toxicity evaluation; mannosylated gelatin; pharmacokinetics toxicity ... See more keywords
Preliminary Toxicity Evaluation of a Porphyrin Photosensitizer in an Alternative Preclinical Model
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043131
Abstract: In photodynamic therapy (PDT), a photosensitizer (PS) excited with a specific wavelength, and in the presence of oxygen, gives rise to photochemical reactions that lead to cell damage. Over the past few years, larval stages… read more here.
Keywords: evaluation porphyrin; toxicity; preliminary toxicity; model ... See more keywords
In Vitro Systems for Toxicity Evaluation of Microbial Volatile Organic Compounds on Humans: Current Status and Trends.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of fungi"
DOI: 10.3390/jof8010075
Abstract: Microbial volatile organic compounds (mVOC) are metabolic products and by-products of bacteria and fungi. They play an important role in the biosphere: They are responsible for inter- and intra-species communication and can positively or negatively… read more here.
Keywords: vitro systems; organic compounds; systems toxicity; volatile organic ... See more keywords
pH Sensitive Pluronic Acid/Agarose-Hydrogels as Controlled Drug Delivery Carriers: Design, Characterization and Toxicity Evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061218
Abstract: The objective of this study was to fabricate and evaluate a pH sensitive cross-linked polymeric network through the free radical polymerization technique for the model drug, cyclophosphamide, used in the treatment of non-Hodgkin’s lymphoma. The… read more here.
Keywords: toxicity evaluation; drug; toxicity; pluronic acid ... See more keywords