Novel risk factor for valganciclovir toxicity—NUDT15 genetic variant
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DOI: 10.1111/tid.13799
Abstract: Recent “in vitro” studies describe nucleoside diphosphate–linked moiety X-type motif 15 (NUDT15) enzyme to be involved in the metabolismofganciclovir. 1,2 Wereportsevereleukopeniaduringther-apy with valganciclovir in a recent kidney transplant recipient with NUDT15 geneticvariation.Thiscasereportisthefirsttosubstantiatea theoretical postulate of… read more here.
Keywords: factor valganciclovir; toxicity nudt15; valganciclovir toxicity; risk factor ... See more keywords