Contamination levels, toxicity profiles, and emission sources of polycyclic aromatic hydrocarbons (PAHs) in the soils of an emerging industrial town and its environs in the Southeastern Nigeria
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-017-6347-y
Abstract: Polycyclic aromatic hydrocarbon (PAH) concentrations in Nnewi and its environs were determined. Soil samples were extracted by sonication using hexane:dichloromethane (3:1) mixture and determined by gas chromatography-flame ionization detection. The total PAHs concentrations (μg/kg) were… read more here.
Keywords: levels toxicity; toxicity; contamination levels; toxicity profiles ... See more keywords
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205591119
Abstract: Significance We have developed an approach to define the size of small aggregates involved in neurodegenerative disorders at ∼4 nm precision in live cells and in pathological model mouse tissues. We show that aggregates below… read more here.
Keywords: different synucleinopathies; toxicity; super resolution; distinct toxicity ... See more keywords
toxCSM: comprehensive prediction of small molecule toxicity profiles
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac337
Abstract: Drug discovery is a lengthy, costly and high-risk endeavour that is further convoluted by high attrition rates in later development stages. Toxicity has been one of the main causes of failure during clinical trials, increasing… read more here.
Keywords: small molecule; prediction small; toxcsm comprehensive; comprehensive prediction ... See more keywords
Toxicity Profiles of Fractionated Radiotherapy, Contemporary Stereotactic Radiosurgery, and Transsphenoidal Surgery in Nonfunctioning Pituitary Macroadenomas
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DOI: 10.3390/cancers11111658
Abstract: Background: Here, we compared the toxicity profiles of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery used to treat nonfunctioning pituitary macroadenomas. Methods: We included the data of patients with nonfunctioning pituitary… read more here.
Keywords: toxicity profiles; transsphenoidal surgery; pituitary macroadenomas; nonfunctioning pituitary ... See more keywords