Articles with "toxicity rats" as a keyword



Novel insights into the potential mechanisms underlying carbendazim‐induced hepatorenal toxicity in rats

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23079

Abstract: Carbendazim (CBZ) is a common environmental pollutant that can contaminate food and water and severely damage human health. Some studies revealed the adverse effect of CBZ on different organs, but its detailed toxicity mechanism has… read more here.

Keywords: carbendazim; induced hepatorenal; cbz; hepatorenal toxicity ... See more keywords

Diacerein modulates TLR4/ NF-κB/IL-1β and TRPC1/CHOP signalling pathways in gentamicin-induced parotid toxicity in rats.

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Published in 2023 at "Journal of cellular and molecular medicine"

DOI: 10.1111/jcmm.17791

Abstract: The present study aimed to identify the possible protective effect of diacerein (DIA) on gentamicin (GNT)-induced parotid toxicity in rats. DIA was administered in the presence and absence of GNT. Thirty-two Wistar adult male rats… read more here.

Keywords: chop; tlr4 trpc1; induced parotid; toxicity rats ... See more keywords

Ultrasonographic and histopathological investigation of the effect of N-acetylcysteine on doxorubicin-induced ovarian and uterine toxicity in rats

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Published in 2024 at "Journal of Ovarian Research"

DOI: 10.1186/s13048-024-01459-4

Abstract: This study aimed to investigate the mitigating effect of N-acetylcysteine (NAC) on doxorubicin (DOX)-induced ovarian and uterine toxicity in rats using laboratory tests, ultrasonographic (US) imaging, and histopathology analysis. Forty-eight rats were divided into six… read more here.

Keywords: induced ovarian; group; effect acetylcysteine; uterine toxicity ... See more keywords

Investigation of the Possible Protective Effect of N-Acetylcysteine (NAC) against Irinotecan (CPT-11)-Induced Toxicity in Rats

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Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11112219

Abstract: Irinotecan (CPT-11) is a chemotherapeutic agent involved in the treatment regimens for several malignancies such as colorectal cancer. N-acetylcysteine (NAC) is a strong antioxidant and anti-inflammatory agent used in the treatment of several diseases related… read more here.

Keywords: effect; acetylcysteine nac; cpt; toxicity rats ... See more keywords

Protective Effect of Terminalia catappa Leaves and Terminalia chebula Fruits on the Enzymatic and Non-enzymatic Anti-oxidant Levels in the Doxorubicin Induced Toxicity Rats

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Published in 2019 at "Pharmacognosy Journal"

DOI: 10.5530/pj.2019.11.51

Abstract: Background: Oxidative stress plays an important role in chronic complications of diabetes, cancer, liver disorder etc. The free radicals such as superoxide anions, hydrogen peroxides are causing the oxidative stress and it involves the cellular… read more here.

Keywords: induced toxicity; toxicity rats; catappa leaves; chebula fruits ... See more keywords