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Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2439
Abstract: Yatakemycin (YTM) is an extraordinarily toxic DNA alkylating agent with potent antimicrobial and antitumor properties and the most recent addition to the CC-1065 and duocarmycin family of natural products. While bulky DNA lesions the size…
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Keywords:
toxicity repair;
dna adducts;
toxicity;
repair dna ... See more keywords