Biochemical alterations in duckweed and algae induced by carrier solvents: Selection of an appropriate solvent in toxicity testing.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3804
Abstract: Carrier solvents are often used in aquatic toxicity testing for test chemicals with hydrophobic properties. However, the knowledge of solvent effects on test organisms remains limited. The present study aimed to determine the biochemical effects… read more here.
Keywords: toxicity; toxicity testing; carrier solvents; test species ... See more keywords
A Comparison of the chemical sensitivities between in vitro and in vivo propagated juvenile freshwater mussels: Implications for standard toxicity testing.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4270
Abstract: Unionid mussels are ecologically important and are globally imperiled. Toxicants contribute to mussel declines, and toxicity tests using juvenile mussels-a sensitive life stage-are valuable in determining thresholds used to set water quality criteria. In vitro… read more here.
Keywords: toxicity testing; vitro vivo; toxicity; vivo propagated ... See more keywords
Untargeted metabolomics of neuronal cell culture: A model system for the toxicity testing of insecticide chemical exposure
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3498
Abstract: Toxicity testing is essential for the protection of human health from exposure to toxic environmental chemicals. As traditional toxicity testing is carried out using animal models, mammalian cell culture models are becoming an increasingly attractive… read more here.
Keywords: cell culture; toxicity testing; cell; exposure ... See more keywords
Defining and Controlling Exposure During In Vitro Toxicity Testing and the Potential of Passive Dosing.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2015_5017
Abstract: Toxicity testing using in vitro bioassays is assuming an increasingly important role. Nevertheless, several issues remain with regard to their proper application, which mainly relate to the proper definition and control of the test chemical(s)… read more here.
Keywords: toxicity testing; vitro toxicity; exposure; toxicity ... See more keywords
Evaluation of dimethyl sulfoxide (DMSO) as a co-solvent for toxicity testing of hydrophobic organic compounds
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology"
DOI: 10.1007/s10646-019-02107-0
Abstract: Toxicity testing of hydrophobic compounds with low aqueous solubility remains challenging. Dimethyl sulfoxide (DMSO) is widely used as a co-solvent for toxicity testing of hydrophobic chemicals, but it may modulate chemical toxicity patterns. In this… read more here.
Keywords: toxicity testing; testing hydrophobic; solvent toxicity; toxicity ... See more keywords
Investigation of clearance rate as an endpoint in toxicity testing with freshwater mussels (Unionidae).
Sign Up to like & getrecommendations! Published in 2018 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.07.054
Abstract: The implementation of ecologically relevant sub-lethal endpoints in toxicity testing with freshwater mussels can provide valuable information during risk assessment, especially since these organisms are often exposed to low levels of contaminants. This study examined… read more here.
Keywords: toxicity testing; freshwater mussels; clearance rate; testing freshwater ... See more keywords
Development a high-throughput zebrafish embryo acute toxicity testing method based on OECD TG 236
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2022.2099772
Abstract: Abstract The Organization for Economic Co-operation and Development (OECD）Test Guideline (TG) 236 for zebrafish embryo acute toxicity testing was adopted for chemical toxicity assessment in 2013. Due to the increasing demand for prediction and evaluation… read more here.
Keywords: zebrafish embryo; toxicity testing; toxicity; acute toxicity ... See more keywords
Toxicity testing is evolving!
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology research"
DOI: 10.1093/toxres/tfaa011
Abstract: The efficient management of the continuously increasing number of chemical substances used in today's society is assuming greater importance than ever before. Toxicity testing plays a key role in the regulatory decisions of agencies and… read more here.
Keywords: toxicity; toxicity testing; need; testing evolving ... See more keywords
Toxicity testing of nonwovens used for production of respiratory protective equipment.
Sign Up to like & getrecommendations! Published in 2023 at "Central European journal of public health"
DOI: 10.21101/cejph.a7429
Abstract: OBJECTIVES During the covid-19 pandemic, protective equipment such as respirators and masks were widely used to protect respiratory tract. This disposable protective equipment is usually made from plastic fibre-based nonwoven fabrics. If used masks and… read more here.
Keywords: toxicity testing; protective equipment; testing nonwovens; equipment ... See more keywords
Human Pluripotent Stem Cells: A Unique Tool for Toxicity Testing in Pancreatic Progenitor and Endocrine Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.604998
Abstract: Diabetes prevalence is increasing worldwide, and epidemiological studies report an association between diabetes incidence and environmental pollutant exposure. There are >84,000 chemicals in commerce, many of which are released into the environment without a clear… read more here.
Keywords: toxicity testing; human pluripotent; toxicity; endocrine cells ... See more keywords
A Framework for Ecotoxicity Testing in the 21st Century: Ecotox21
Sign Up to like & getrecommendations! Published in 2019 at "Applied Sciences"
DOI: 10.3390/app9030428
Abstract: To reduce the considerable investments of toxicity testing and protecting animal welfare, a new toxicity testing strategy based on response pathways of human cell lines has been proposed in the United States to evaluate the… read more here.
Keywords: ecotoxicity; toxicity testing; ecotoxicity testing; 21st century ... See more keywords