Fertility and early embryonic development toxicity and toxicokinetic study of KFP‐H008 in Sprague–Dawley rats
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DOI: 10.1002/bdr2.2002
Abstract: The novel potassium competitive acid blocker, KFP‐H008, developed to overcome the shortcomings of proton pump inhibitors. In this study, KFP‐H008 was administered by oral gavage at doses of 0 (control), 15, 45, and 150 mg/kg to… read more here.
Keywords: sprague dawley; dawley rats; toxicokinetic study; study kfp ... See more keywords
Acute toxicity, 28-day repeated-dose toxicity and toxicokinetic study of timosaponin BII in beagle dogs.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.1993834
Abstract: The safety evaluation of timosaponin BII (TBII) in beagle dogs with toxicokinetic study was performed. For the acute oral toxicity study, the minimum lethal dose (MLD) of TBII was more than 2000 mg/kg and suggested the… read more here.
Keywords: beagle dogs; timosaponin bii; study; toxicity ... See more keywords
Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study
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DOI: 10.3390/molecules25132964
Abstract: In this study, a specific and sensitive method of liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was developed for the determination of penconazole enantiomers in rat plasma. The enantioseparation was achieved on a Chiralpak… read more here.
Keywords: rat plasma; determination penconazole; study; toxicokinetic study ... See more keywords