Biocompatibility Evolves: Phenomenology to Toxicology to Regeneration.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202002153
Abstract: The word "biocompatibility," is inconsistent with the observations of healing for so-called biocompatible biomaterials. The vast majority of the millions of medical implants in humans today, presumably "biocompatible," are walled off by a dense, avascular,… read more here.
Keywords: foreign body; evolves phenomenology; biocompatibility; biocompatibility evolves ... See more keywords
Toxicity and Biocompatibility of Liquid Metals
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201924
Abstract: Recently, room‐temperature liquid metals have attracted increasing attention from researchers owing to their excellent material properties. Systematic interpretation of the potential toxicity issues involved is essential for a wide range of applications, especially in the… read more here.
Keywords: liquid metal; toxicology; toxicity; liquid metals ... See more keywords
Machine Learning‐Enabled Drug‐Induced Toxicity Prediction
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202413405
Abstract: Unexpected toxicity has become a significant obstacle to drug candidate development, accounting for 30% of drug discovery failures. Traditional toxicity assessment through animal testing is costly and time‐consuming. Big data and artificial intelligence (AI), especially… read more here.
Keywords: induced toxicity; toxicity prediction; drug; toxicity ... See more keywords
The impact of fellowship‐trained medical toxicology faculty on emergency medicine resident in‐training examination scores
Sign Up to like & getrecommendations! Published in 2023 at "AEM Education and Training"
DOI: 10.1002/aet2.10840
Abstract: The American Board of Emergency Medicine (ABEM) In Training Exam (ITE) gauges residents' medical knowledge and has been shown to correlate with subsequent performance on the ABEM board qualifying examination. It is common for emergency… read more here.
Keywords: toxicology; faculty; emergency medicine; examination ... See more keywords
Application of natural compounds–based gold nanoparticles for the treatment of hemolytic anemia in an anemic mouse model: Formulation of a novel drug from relationship between the nanotechnology and hematology sciences
Sign Up to like & getrecommendations! Published in 2020 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.5475
Abstract: Department of Toxicology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Division of Toxicology, Department of Comparative Biosciences, Faculty of Veterinary… read more here.
Keywords: medicine; hematology; university; tehran ... See more keywords
Comments on “Reproductive toxicology studies supporting the safety of molindone, a dopamine receptor antagonist” (Gopalakrishnan et al., Birth Defects Research. 2018; 110(16):1250–1262)
Sign Up to like & getrecommendations! Published in 2019 at "Birth Defects Research"
DOI: 10.1002/bdr2.1471
Abstract: This article reports on a standard set of developmental and reproductive toxicity studies with molindone. I submit that the presented data does not support the major conclusion as stated in the Abstract (“Molindone was not… read more here.
Keywords: birth defects; molindone; safety molindone; toxicity ... See more keywords
Use of computational toxicology models to predict toxicological points of departure: A case study with triazine herbicides
Sign Up to like & getrecommendations! Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2144
Abstract: Atrazine simazine and propazine, widely used triazine herbicides on food crops and in residential areas, disrupt the neuroendocrine system raising human health concerns. USEPA developed a PBPK model based on triazine common Mode of Action… read more here.
Keywords: points departure; toxicology; use computational; triazine herbicides ... See more keywords
Use of a 3D inkjet‐printed model to access dust particle toxicology in the human alveolar barrier
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28220
Abstract: Fine dust particles in the air travel into our body via the airway tract and cause severe respiratory diseases. Thus, the analysis of the effects of dust particles on the respiratory system has been receiving… read more here.
Keywords: inkjet printed; toxicology; alveolar barrier; dust particles ... See more keywords
Introduction to special section on using pools to generate Good Laboratory Practice tox or other non‐clinical material to accelerate development timelines
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Progress"
DOI: 10.1002/btpr.2583
Abstract: In this issue, we present a special section on the use of CHO cell pools to produce material for Investigational New Drug (IND)-enabling Good Laboratory Practice (GLP) toxicology studies and/or other non-clinical early development studies.… read more here.
Keywords: non clinical; toxicology; section; development ... See more keywords
Proceedings of International Conference on Cell Death in Cancer and Toxicology
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DOI: 10.1002/cam4.1413
Abstract: Apoptotic cells can produce signals to instruct cells in their local environment, including factors that stimulate proliferation. This apoptosisinduced proliferation has been shown to play important roles in tissue regeneration, tumor growth and relapse. We… read more here.
Keywords: apoptosis; toxicology; cancer; cell death ... See more keywords
Development and validation of a rapid LC-MS/MS method for the detection of 182 novel psychoactive substances in whole blood.
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DOI: 10.1002/dta.3170
Abstract: INTRODUCTION The analysis of novel psychoactive substances (NPS) represents a challenge in forensic toxicology, due to the high number of compounds characterized by different structures and physicochemical properties both among different subclasses and within a… read more here.
Keywords: detection; validation; method; novel psychoactive ... See more keywords