Death by translation: ribosome‐assisted degradation of mRNA by endonuclease toxins
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12715
Abstract: Like other forms of life, bacteria utilize a variety of mechanisms to survive stress. Some of these mechanisms mitigate the physiological impact of the stress, whereas others enable cells to simply wait out the stressful… read more here.
Keywords: endonuclease; yhav; stress; toxin ... See more keywords
Identification and functional characterization of a bacterial homologue of Zeta toxin in Leishmania donovani
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13429
Abstract: Zeta‐toxin is a cognate toxin of epsilon antitoxin of prokaryotic Type II toxin‐antitoxin system (TA) and play an important role in cell death. An orthologue of bacterial‐zeta‐toxin (BzT) was identified in Leishmania donovani with similar… read more here.
Keywords: leishmania donovani; zeta toxin; toxin; cell death ... See more keywords
Bacterial Toxin‐Responsive Biomimetic Nanobubbles for Precision Photodynamic Therapy against Bacterial Infections
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200698
Abstract: With few options available for the effective treatment of multidrug‐resistant bacteria, photodynamic therapy (PDT) has emerged as a promising therapeutic strategy that does not promote the development of antibiotic resistance. Unfortunately, the beneficial bactericidal effect… read more here.
Keywords: responsive biomimetic; toxin; photodynamic therapy; biomimetic nanobubbles ... See more keywords
High yield purification and first structural characterization of the full‐length bacterial toxin CNF1
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Progress"
DOI: 10.1002/btpr.2574
Abstract: The Cytotoxic Necrotizing Factor 1 (CNF1) is a bacterial toxin secreted by certain Escherichia coli strains causing severe pathologies, making it a protein of pivotal interest in toxicology. In parallel, the CNF1 capability to influence… read more here.
Keywords: protein; full length; bacterial toxin; toxin ... See more keywords
Endoplasmic reticulum stress is involved in the T‐2 toxin‐induced apoptosis in goat endometrium epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3655
Abstract: T‐2 toxin is one of the trichothecene mycotoxins commonly found in animal feed and agricultural products. Ingestion of T‐2 toxin by animals results in acute and chronic diseases, as well as reproductive failure. This study… read more here.
Keywords: epithelial cells; endometrium epithelial; apoptosis; induced apoptosis ... See more keywords
Cytotoxic and apoptotic properties of a novel nano‐toxin formulation based on biologically synthesized silver nanoparticle loaded with recombinant truncated pseudomonas exotoxin A
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29265
Abstract: Bacterial toxins have received a great deal of attention in the development of antitumor agents. Currently, these protein toxins were used in the immunotoxins as a cancer therapy strategy. Despite the successful use of immunotoxins,… read more here.
Keywords: pseudomonas exotoxin; truncated pseudomonas; toxin; nano toxin ... See more keywords
Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a0419-123r
Abstract: Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and… read more here.
Keywords: ricin; ricin toxin; kupffer cells; liver sinusoidal ... See more keywords
Investigating the role of Bacillus subtilis type II toxin-antitoxin system in drought stress survival.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of basic microbiology"
DOI: 10.1002/jobm.202300120
Abstract: Toxin-antitoxin (TA) systems, present in plasmids and bacterial chromosomes, are widespread in bacteria such as Bacillus subtilis and are known to be involved in growth regulation, bacterial tolerance to environmental stress conditions as well as… read more here.
Keywords: stress; 548 ethylene; toxin; antitoxin ... See more keywords
Protective mechanisms of three antioxidants against T-2 toxin-induced muscle proteins deterioration in shrimp.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11851
Abstract: Quercetin (Q), tea polyphenols (TP) and rutin (R) are the most widely used plant-derived active ingredients that possess antioxidant, anti-inflammatory and anti-tumour properties, and can reduce the muscle damage caused by mycotoxins. However, few studies… read more here.
Keywords: muscle proteins; muscle; toxin; three antioxidants ... See more keywords
Recombinant Limosilactobacillus (Lactobacillus) delivering nanobodies against Clostridium perfringens NetB and alpha toxin confers potential protection from necrotic enteritis
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1270
Abstract: Necrotic enteritis (NE), caused by Clostridium perfringens, is an intestinal disease with devastating economic losses to the poultry industry. NE is a complex disease and predisposing factors that compromise gut integrity are required to facilitate… read more here.
Keywords: limosilactobacillus lactobacillus; necrotic enteritis; clostridium perfringens; toxin ... See more keywords
LIVECHART Patient‐Reported Outcome Tool for Botulinum Toxin Treatment in Cervical Dystonia
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13401
Abstract: Many tools used for recording the response to botulinum toxin treatment are disease‐specific, observer‐based and cumbersome to implement in service settings, especially where clinics treat a variety of disorders. Physicians, clinics, researchers, and patients themselves… read more here.
Keywords: patient; toxin treatment; toxin; botulinum toxin ... See more keywords