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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212664120
Abstract: Many bacteria possess dynamic filaments called Type IV pili (T4P) that perform diverse functions in colonization and dissemination, including host cell adhesion, DNA uptake, and secretion of protein substrates-exoproteins-from the periplasm to the extracellular space.…
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Keywords:
toxin coregulated;
vibrio cholerae;
secretion;
tcpf ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175170
Abstract: The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V. cholerae to be non-toxigenic and…
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Keywords:
production;
vaccine;
toxin coregulated;
oral cholera ... See more keywords