A Severe Clinical Case of Ehrlichia canis and Toxoplasma gondii in a Dog (With the First Morphological Detection of Tachyzoites in Peripheral Blood)
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.70380
Abstract: ABSTRACT Vector‐borne pathogens (VBPs) are frequently identified in domestic dogs, particularly in endemic areas or in individuals lacking protection from anti‐feeding products. Diagnostic procedures in veterinary clinics for symptomatic animals primarily include rapid serological assays;… read more here.
Keywords: dog; ehrlichia canis; toxoplasma; blood ... See more keywords
Comparative and analytical study on active toxoplasmosis to assess the IgG avidity in correlation to serological profile in a cohort of Egyptian patients
Sign Up to like & getrecommendations! Published in 2017 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-017-2501-8
Abstract: Proper diagnosis of toxoplasmosis is very important for proper treatment in manifested cases and to prevent congenital toxoplasmosis in case of pregnancy. Screening of 180 pregnant females by automated immune assay for Toxoplasma IgG and… read more here.
Keywords: igg avidity; toxoplasmosis; toxoplasma; igm ... See more keywords
Designing Diagnostic Kit for Toxoplasma gondii Based on GRA7, SAG1, and ROP1 Antigens: An In Silico Strategy
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-020-10021-x
Abstract: Toxoplasma gondii is an intracellular protozoan that infects a wide range of mammalians. Commercial diagnostic kits usually use the whole parasite antigen to, which can reduce the specificity of the test. B-cell epitopes are antigenic… read more here.
Keywords: rop1; toxoplasma; gondii; structure ... See more keywords
Toxoplasma gondii: manipulation of host cell machinery in the journey from intestine to brain
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2017.04.001
Abstract: Abstract Question From previous work, this group had discovered that infection of dendritic cells (DC) caused by the intracellular parasite ( Toxoplasma gondii) induced a hyper-migratory state in DC which was a possible mechanism of… read more here.
Keywords: infection; gondii; toxoplasma; gaba ... See more keywords
Identification of a Master Regulator of Differentiation in Toxoplasma
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2019.12.013
Abstract: Summary Toxoplasma gondii chronically infects a quarter of the world’s population, and its recrudescence can cause life-threatening disease in immunocompromised individuals and recurrent ocular lesions in the immunocompetent. Acute-stage tachyzoites differentiate into chronic-stage bradyzoites, which… read more here.
Keywords: identification master; regulator differentiation; differentiation toxoplasma; toxoplasma ... See more keywords
Toxoplasma gondii infection and spontaneous abortion: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105070
Abstract: Toxoplasmosis is one of the most common parasitic infections in humans, which is caused by Toxoplasma gondii. It is usually asymptomatic but primary infection in a pregnant woman can cause severe consequences in the fetus… read more here.
Keywords: spontaneous abortion; abortion; gondii infection; infection ... See more keywords
Deletion of splicing factor Cdc5 in Toxoplasma disrupts transcriptome integrity, induces abortive bradyzoite formation, and prevents acute infection in mice
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58805-3
Abstract: Toxoplasma gondii, an apicomplexan parasite, has over 75% of its genes containing introns; however, the role of RNA splicing in regulating gene expression remains unclear. Here, we demonstrate that the pre-mRNA splicing factor Cdc5 is… read more here.
Keywords: splicing factor; transcriptome integrity; factor cdc5; toxoplasma ... See more keywords
A P5-ATPase, TgFLP12, diverging from plant chloroplast lipid transporters mediates apicoplast fatty export in Toxoplasma
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61155-9
Abstract: Toxoplasma gondii, an apicomplexan parasite and agent of the human disease toxoplasmosis, possesses a non-photosynthetic relic plastid, named the apicoplast. Thought to be evolved from a red algal plastid, the apicoplast houses major metabolic pathways,… read more here.
Keywords: chloroplast lipid; tgflp12; toxoplasma; plant chloroplast ... See more keywords
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection
Sign Up to like & getrecommendations! Published in 2025 at "Nature Microbiology"
DOI: 10.1038/s41564-025-02193-3
Abstract: Membrane contact sites (MCS) are essential for organelle communication in eukaryotic cells. Pathogens also establish MCS with host organelles, but the mechanisms underlying these interactions and their role in infection remain poorly understood. Here, using… read more here.
Keywords: contact sites; host; effector; infection ... See more keywords
The master of Toxoplasma differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Microbiology"
DOI: 10.1038/s41579-020-0329-8
Abstract: This study identifies a master regulator of chronic-stage differentiation in Toxoplasma gondii. read more here.
Keywords: toxoplasma differentiation; toxoplasma; microbiology; differentiation ... See more keywords
Seroprevalence of Toxoplasma gondii and Borrelia burgdorferi infections in patients with multiple sclerosis in Poland
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-61714-y
Abstract: Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system that affects mainly young people. It is believed that the autoimmune process observed in the pathogenesis of MS is influenced by a… read more here.
Keywords: toxoplasma gondii; multiple sclerosis; gondii borrelia; toxoplasma ... See more keywords