Comparative and analytical study on active toxoplasmosis to assess the IgG avidity in correlation to serological profile in a cohort of Egyptian patients
Sign Up to like & getrecommendations! Published in 2017 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-017-2501-8
Abstract: Proper diagnosis of toxoplasmosis is very important for proper treatment in manifested cases and to prevent congenital toxoplasmosis in case of pregnancy. Screening of 180 pregnant females by automated immune assay for Toxoplasma IgG and… read more here.
Keywords: igg avidity; toxoplasmosis; toxoplasma; igm ... See more keywords
Designing Diagnostic Kit for Toxoplasma gondii Based on GRA7, SAG1, and ROP1 Antigens: An In Silico Strategy
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-020-10021-x
Abstract: Toxoplasma gondii is an intracellular protozoan that infects a wide range of mammalians. Commercial diagnostic kits usually use the whole parasite antigen to, which can reduce the specificity of the test. B-cell epitopes are antigenic… read more here.
Keywords: rop1; toxoplasma; gondii; structure ... See more keywords
Toxoplasma gondii: manipulation of host cell machinery in the journey from intestine to brain
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2017.04.001
Abstract: Abstract Question From previous work, this group had discovered that infection of dendritic cells (DC) caused by the intracellular parasite ( Toxoplasma gondii) induced a hyper-migratory state in DC which was a possible mechanism of… read more here.
Keywords: infection; gondii; toxoplasma; gaba ... See more keywords
Identification of a Master Regulator of Differentiation in Toxoplasma
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2019.12.013
Abstract: Summary Toxoplasma gondii chronically infects a quarter of the world’s population, and its recrudescence can cause life-threatening disease in immunocompromised individuals and recurrent ocular lesions in the immunocompetent. Acute-stage tachyzoites differentiate into chronic-stage bradyzoites, which… read more here.
Keywords: identification master; regulator differentiation; differentiation toxoplasma; toxoplasma ... See more keywords
Toxoplasma gondii infection and spontaneous abortion: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105070
Abstract: Toxoplasmosis is one of the most common parasitic infections in humans, which is caused by Toxoplasma gondii. It is usually asymptomatic but primary infection in a pregnant woman can cause severe consequences in the fetus… read more here.
Keywords: spontaneous abortion; abortion; gondii infection; infection ... See more keywords
The master of Toxoplasma differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Microbiology"
DOI: 10.1038/s41579-020-0329-8
Abstract: This study identifies a master regulator of chronic-stage differentiation in Toxoplasma gondii. read more here.
Keywords: toxoplasma differentiation; toxoplasma; microbiology; differentiation ... See more keywords
Assessing viability and infectivity of foodborne and waterborne stages (cysts/oocysts) of Giardia duodenalis, Cryptosporidium spp., and Toxoplasma gondii: a review of methods
Sign Up to like & getrecommendations! Published in 2018 at "Parasite"
DOI: 10.1051/parasite/2018009
Abstract: Giardia duodenalis, Cryptosporidium spp. and Toxoplasma gondii are protozoan parasites that have been highlighted as emerging foodborne pathogens by the Food and Agriculture Organization of the United Nations and the World Health Organization. According to… read more here.
Keywords: gondii; cryptosporidium spp; toxoplasma; cryptosporidium ... See more keywords
Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice
Sign Up to like & getrecommendations! Published in 2020 at "Parasite"
DOI: 10.1051/parasite/2020021
Abstract: Toxoplasma gondii is a threat for immunocompromized individuals, and no treatment is available for enhancing immunity against infection. Molecular adjuvants may improve the efficacy of DNA vaccine-induced T cell immunity. Here, we report that cocktailed… read more here.
Keywords: immunity; gondii; infection; rop5 rop18 ... See more keywords
Anatomical distribution of Toxoplasma gondii in naturally and experimentally infected lambs
Sign Up to like & getrecommendations! Published in 2022 at "Parasite"
DOI: 10.1051/parasite/2022001
Abstract: Consumption of raw or undercooked meat containing Toxoplasma gondii tissue cysts is one of the main sources of infection for humans worldwide. Among the various species intended for human consumption, sheep appear to be a… read more here.
Keywords: gondii naturally; distribution toxoplasma; anatomical distribution; toxoplasma ... See more keywords
Serological diagnosis of toxoplasmosis: evaluation of the commercial test recomLine Toxoplasma IgG immunoblot (Mikrogen) based on recombinant antigens
Sign Up to like & getrecommendations! Published in 2022 at "Parasite"
DOI: 10.1051/parasite/2022050
Abstract: Background: IgG detection to determine immune status to Toxoplasma gondii infection and seroconversion mainly relies on ELISA techniques and, if necessary, on a confirmatory test, Western blot. This study evaluated the performance of the recomLine… read more here.
Keywords: recomline; test; sera; group ... See more keywords
Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2022.2112576
Abstract: Abstract A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the… read more here.
Keywords: therapy pyrimethamine; toxoplasma; standard therapy; toxoplasma gondii ... See more keywords