Prevalence and clinical impact of TP53 germline mutations in Chinese women with breast cancer
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DOI: 10.1002/ijc.32424
Abstract: The prevalence and clinical relevance of TP53 germline mutations in a large unselected breast cancer series are largely unknown. Here, we determined TP53 germline mutations in a large cohort of 10,053 unselected breast cancer patients… read more here.
Keywords: cancer; tp53 germline; germline mutations; breast cancer ... See more keywords
Characteristics of Li‐Fraumeni syndrome in Japan: A review study by the special committee of JSHT
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DOI: 10.1111/cas.14919
Abstract: Li‐Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome, and the majority of patients with LFS have been identified with germline variants in the p53 tumor suppressor (TP53) gene. In the past three decades, considerable… read more here.
Keywords: fraumeni syndrome; tp53 germline; characteristics fraumeni; japan ... See more keywords