ROS modifiers and NOX4 affect the expression of the survivin‐associated radio‐adaptive response
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DOI: 10.1016/j.freeradbiomed.2018.04.547
Abstract: Abstract The survivin‐associated radio‐adaptive response can be induced following exposure to ionizing radiation in the dose range from 5 to 100 mGy, and its magnitude of expression is dependent upon the TP53 mutational status of… read more here.
Keywords: response; survivin; adaptive response; tp53 mut ... See more keywords
Enhanced Survival of High-Risk Medulloblastoma-Bearing Mice after Multimodal Treatment with Radiotherapy, Decitabine, and Abacavir
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DOI: 10.3390/ijms23073815
Abstract: Children with high-risk SHH/TP53-mut and Group 3 medulloblastoma (MB) have a 5-year overall survival of only 40%. Innovative approaches to enhance survival while preventing adverse effects are urgently needed. We investigated an innovative therapy approach… read more here.
Keywords: tp53 mut; therapy; shh tp53; bearing mice ... See more keywords