Abstract IA08: Personalizing HNSCC treatment based on TP53 mutational status
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DOI: 10.1158/1557-3265.aacrahns17-ia08
Abstract: Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer deaths worldwide, and resistance to standard treatments with radiation/chemotherapy accounts for the majority of HNSCC deaths. Mutation of TP53 occurs in 60-85%… read more here.
Keywords: tp53 mutational; hnscc; mutational status; cancer ... See more keywords
Abstract A004: TP53 mutational landscape in non-cancerous endometrium during the lifespan of Black and White individuals
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DOI: 10.1158/1557-3265.endo24-a004
Abstract: Background TP53 somatic mutations accumulate and clonally expand in histologically normal tissues with aging, however, little is known about this process and how it influences cancer development. Within endometrial carcinoma, TP53 mutations tend to be… read more here.
Keywords: white individuals; cancer; tp53 mutational; black white ... See more keywords