Current review of TP53 pathogenic germline variants in breast cancer patients outside Li‐Fraumeni syndrome
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DOI: 10.1002/humu.23656
Abstract: Pathogenic germline variants in TP53 predispose carriers to the multi‐cancer Li‐Fraumeni syndrome (LFS). Widespread multigene panel testing is identifying TP53 pathogenic variants in breast cancer patients outside the strict clinical criteria recommended for LFS testing.… read more here.
Keywords: cancer; tp53 pathogenic; germline variants; breast cancer ... See more keywords