Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms
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DOI: 10.1080/2162402x.2017.1404216
Abstract: ABSTRACT Loss or mutation of TP53 has been linked to alterations in anti-tumor immunity as well as dysregulation of cell cycle and apoptosis. We explored immunologic effects and mechanisms following restoration of wild-type human TP53… read more here.
Keywords: sting dependent; tumor immunity; anti tumor; tp53 sting ... See more keywords