TP53 inhibitor PFTα increases the sensitivity of arsenic trioxide in TP53 wildtype tumor cells
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DOI: 10.1002/2211-5463.13366
Abstract: Arsenic trioxide (ATO) has been shown to be effective in treating acute promyelocytic leukemia. TP53 mutated/null tumor cells are more sensitive to ATO treatment compared to tumor cells carrying wildtype TP53 gene copies. However, it… read more here.
Keywords: pft; tumor cells; tp53; tp53 wildtype ... See more keywords