Mutations in TP73 cause impaired mucociliary clearance and lissencephaly.
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DOI: 10.1016/j.ajhg.2021.05.002
Abstract: TP73 belongs to the TP53 family of transcription factors and has therefore been well studied in cancer research. Studies in mice, however, have revealed non-oncogenic activities related to multiciliogenesis. Utilizing whole-exome sequencing analysis in a… read more here.
Keywords: tp73 cause; lissencephaly; mucociliary clearance; microscopy ... See more keywords