MRTFA Augments Megakaryocyte Maturation By Enhancing the SRF Regulatory Axis
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DOI: 10.1182/blood-2018-99-118954
Abstract: Pediatric non-Down Syndrome acute megakaryoblastic leukemia (AMKL), a disease where megakaryocyte (MK) maturation is blocked, has a very poor prognosis. In 13% of AMKL cases of this type, the transcriptional co-factor MRTFA is expressed as… read more here.
Keywords: srf mrtfa; megakaryopoiesis; tpa induction; mrtfa ... See more keywords