Taurine Reduces tPA (Tissue-Type Plasminogen Activator)-Induced Hemorrhage and Microvascular Thrombosis After Embolic Stroke in Rat
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DOI: 10.1161/strokeaha.118.020747
Abstract: Background and Purpose— Taurine (2-aminoethansulfolic amino acid) exerts neuroprotective actions in experimental stroke. Here, we investigated the effect of taurine in combination with delayed tPA (tissue-type plasminogen activator) on embolic stroke. Methods— Rats subjected to… read more here.
Keywords: combination; tissue type; tpa tissue; hemorrhage ... See more keywords
Angioedema and Hemorrhage After 4.5-Hour tPA (Tissue-Type Plasminogen Activator) Thrombolysis Ameliorated by T541 via Restoring Brain Microvascular Integrity
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DOI: 10.1161/strokeaha.118.021754
Abstract: Background and Purpose— tPA (tissue-type plasminogen activator) is the only recommended intravenous thrombolytic agent for ischemic stroke. However, its application is limited because of increased risk of hemorrhagic transformation beyond the time window. T541 is… read more here.
Keywords: tpa; tpa tissue; hemorrhage; brain ... See more keywords