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Zfra Inhibits the TRAPPC6AΔ-Initiated Pathway of Neurodegeneration

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1 Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232314510

Abstract: When WWOX is downregulated in middle age, aggregation of a protein cascade, including TRAPPC6AΔ (TPC6AΔ), TIAF1, and SH3GLB2, may start to occur, and the event lasts more than 30 years, which results in amyloid precursor… read more here.

Keywords: month old; aggregation; wwox; neurodegeneration ... See more keywords