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   Articles with "tpgs" as a keyword



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Porosity and compatibility of novel polysulfone-/vitamin E-TPGS-grafted composite membrane

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recommendations! Published in 2017 at "Journal of Materials Science"

DOI: 10.1007/s10853-017-1351-8

Abstract: Polysulfone (Psf) hollow fiber membranes are widely used for hemodialysis. Despite its popularity as a biomaterial, the hydrophobicity of the polymer is a major concern for blood contact applications. Various blends of the polymer with… read more here.

Keywords: psf tpgs; psf; polysulfone; vitamin ... See more keywords
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Enhanced anticancer effect of doxorubicin by TPGS-coated liposomes with Bcl-2 siRNA-corona for dual suppression of drug resistance

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recommendations! Published in 2020 at "Asian Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ajps.2019.10.003

Abstract: Multiple drug resistance (MDR) is a tough problem in developing hepatocellular carcinoma (HCC) therapy. Here, we developed TPGS-coated cationic liposomes with Bcl-2 siRNA corona to load doxorubicin (Dox) i.e., Bcl-2 siRNA/Dox-TPGS-LPs, to enhance anticancer effect… read more here.

Keywords: sirna corona; mdr; corona; bcl sirna ... See more keywords
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TPGS/hyaluronic acid dual-functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemo-photothermal combined therapy of superficial tumor

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recommendations! Published in 2020 at "Acta Pharmaceutica Sinica B"

DOI: 10.1016/j.apsb.2020.11.013

Abstract: Abstract Nanoparticles (NPs) have shown potential in cancer therapy, while a single administration conferring a satisfactory outcome is still unavailable. To address this issue, the dissolving microneedles (DMNs) were developed to locally deliver functionalized NPs… read more here.

Keywords: tumor; dissolving microneedles; acid dual; hyaluronic acid ... See more keywords
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Enhanced transmucosal delivery of itraconazole by thiolated d‐&agr;‐tocopheryl poly(ethylene glycol) 1000 succinate micelles for the treatment of Candida albicans

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recommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2017.08.012

Abstract: ABSTRACT This study aimed to investigate the transmucosal delivery of itraconazole (ITZ) by thiolated d‐&agr;‐tocopheryl poly(ethylene glycol) 1000 succinate (TPGS‐Cys) micelles. TPGS‐Cys polymer was successfully synthesized by the simple coupling between carboxyl‐activated TPGS and Cys… read more here.

Keywords: transmucosal delivery; cys micelles; tpgs cys; tpgs tpgs ... See more keywords
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Development of antioxidant and antimicrobial packaging films based on chitosan, D-α-tocopheryl polyethylene glycol 1000 succinate and silicon dioxide nanoparticles

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recommendations! Published in 2020 at "Food Packaging and Shelf Life"

DOI: 10.1016/j.fpsl.2020.100503

Abstract: Abstract Antioxidant and antimicrobial packaging were developed by adding D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) and/or silicon dioxide nanoparticles (nano-SiO2) into chitosan (CS) films. The microstructures, physical and functional properties of CS, CS-TPGS, CS-SiO2 and… read more here.

Keywords: tpgs sio2; antioxidant antimicrobial; antimicrobial packaging; tpgs ... See more keywords
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Effect of surfactant level on properties of celecoxib amorphous solid dispersions

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recommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2018.11.026

Abstract: Abstract The aim of this study was to explore the influence of d -α-tocopheryl polyethylene glycol 1000 succinate (vitamin E TPGS) on the properties of celecoxib (CEL) amorphous solid dispersions (ASDs). ASDs consisting of CEL… read more here.

Keywords: tpgs; effect surfactant; solid dispersions; level ... See more keywords
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Vitamin E d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS) Provokes Cell Death in Human Neuroblastoma SK-N-SH Cells via a Pro-Oxidant Signaling Mechanism.

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recommendations! Published in 2018 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.8b00138

Abstract: Neuroblastoma (NB) is the most common neoplasm during infancy. Unfortunately, NB is still a lethal cancer. Therefore, innovative curative therapies are immediately required. In this study, we showed the prodeath activity of TPGS in human… read more here.

Keywords: pro oxidant; via pro; cell death; cells via ... See more keywords
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Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate.

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recommendations! Published in 2019 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.9b00177

Abstract: We have devised a nanocarrier using "tocopheryl polyethylene glycol succinate (TPGS) conjugated to triphenylphosphonium cation" (TPP-TPGS) for improving the efficacy of doxorubicin hydrochloride (DOX). Triphenylphosphonium cation (TPP) has affinity for an elevated transmembrane potential gradient… read more here.

Keywords: tocopheryl polyethylene; tpp tpgs; drug; polyethylene glycol ... See more keywords
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Design of TPGS-functionalized Cu3BiS3 nanocrystals with strong absorption in the second near-infrared window for radiation therapy enhancement.

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recommendations! Published in 2017 at "Nanoscale"

DOI: 10.1039/c7nr02213a

Abstract: Integrating radiation therapy with high-depth photothermal therapy in the second near-infrared (NIR) window is highly required for efficient treatment of deep-seated tumor cells. Here, we constructed a multifunctional nano-theranostic with bimetallic chalcogenide nanocrystals (NCs) functionalized… read more here.

Keywords: window; radiation therapy; radiation; cu3bis3 ... See more keywords
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Enhanced oral bioavailability of self-assembling curcumin–vitamin E prodrug-nanoparticles by co-nanoprecipitation with vitamin E TPGS

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recommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2020.1821049

Abstract: Abstract Curcumin (CUR), a nontoxic natural compound with potent antitumor activity, was limited in clinical application due to its insolubility and exceedingly low bioavailability. In this study, a novel prodrug-nanoparticle (CSSV/TPGS-NPs) self-assembled by co-nanoprecipitation of… read more here.

Keywords: tpgs nps; cssv tpgs; bioavailability; vitamin tpgs ... See more keywords
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Development and Optimization of TPGS based Stealth Liposome of Doxorubicin Using Box-Behnken Design: Characterization, Hemocompatibility and Cytotoxicity Evaluation in Breast Cancer Cells.

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recommendations! Published in 2021 at "Journal of liposome research"

DOI: 10.1080/08982104.2021.1903034

Abstract: The present work reports the development of doxorubicin (DOX) encapsulated α-Tocopherol polyethylene glycol 1000 succinate (TPGS) coated liposomal system (DOX-LIPO-TPGS) by quality by design (QbD) approach and evaluated for its anticancer and hemocompatibility potential. The… read more here.

Keywords: dox lipo; tpgs; hemocompatibility; dox ... See more keywords