Triphenyl phosphate-induced macrophages dysfunction by activation TLR4-mediated ERK/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23778
Abstract: Triphenyl phosphate (TPHP) is one of the most widely used organic phosphorus flame retardants and is ubiquitous in the environment. Studies have been reported that TPHP may lead to obesity, neurotoxicity and reproductive toxicity, but… read more here.
Keywords: erk pathway; triphenyl phosphate; tlr4 mediated; mediated erk ... See more keywords
Acute exposure to triphenyl phosphate (TPhP) disturbs ocular development and muscular organization in zebrafish larvae.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.04.056
Abstract: Triphenyl phosphate (TPhP) is an organophosphate flame retardant that is frequently detected in the environments. TPhP exposure is known to cause developmental toxicity. However, the underlying molecular mechanisms remain underestimated. In the present study, zebrafish… read more here.
Keywords: exposure; tphp; phosphate tphp; ocular development ... See more keywords
Assessment of the effects of early life exposure to triphenyl phosphate on fear, boldness, aggression, and activity in Japanese quail (Coturnix japonica) chicks.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental pollution"
DOI: 10.1016/j.envpol.2019.113695
Abstract: Triphenyl phosphate (TPHP) is an organophosphate ester (OPE) used as a flame retardant (FR) and plasticizer. TPHP has previously been shown to disrupt behaviour in fish and mammals, but to our knowledge, this is the… read more here.
Keywords: japanese quail; early life; tphp; quail coturnix ... See more keywords
miR-137 and miR-141 regulate tail defects in zebrafish embryos caused by triphenyl phosphate (TPHP).
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.114286
Abstract: Exposure to triphenyl phosphate (TPHP), an organophosphate flame retardants (OPFRs), caused developmental toxicity in zebrafish embryos. However, the underlying molecular mechanism at the epigenetic level is largely unknown. Based on developmental toxicity (i.e., mortality and… read more here.
Keywords: 137 mir; mir 137; mir 141; zebrafish embryos ... See more keywords
Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2019.121732
Abstract: The potential for triphenyl phosphate (TPhP) caused metabolic dysfunction has been documented. However, the relative mechanism of sexual dimorphic disruption on metabolism induced by TPhP remains unclear. Herein, we observed the insulin-sensitizing hormone (adiponectin) was… read more here.
Keywords: disordered adiponectin; metabolism; dysfunction; tphp ... See more keywords
Organophosphorus flame retardant induced hepatotoxicity and brain AChE inhibition on zebrafish (Danio rerio).
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2020.106919
Abstract: Organophosphorus flame retardants (OPFRs) are high production volume (HPV) chemicals. Recent reports reveal that OPFRs are ubiquitous in the environment. Unfortunately, the toxicity profiles for OPFRs on organisms remain limited. Hence, to illustrate the potential… read more here.
Keywords: exposure; organophosphorus flame; term; tphp ... See more keywords
Triphenyl Phosphate (TPHP)-Induced Neurotoxicity in Adult Male Chinese Rare Minnows ( Gobiocypris rarus).
Sign Up to like & getrecommendations! Published in 2018 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b04079
Abstract: The neurotoxicity of triphenyl phosphate (TPHP) in exposed humans and laboratory animals is under debate. The rapid crossing of the blood-brain barrier (BBB) and high distribution of TPHP in fish brains have raised widespread concerns… read more here.
Keywords: neurotoxicity adult; neurotoxicity; tphp; phosphate tphp ... See more keywords
High accumulation of microplastic fibers in fish hindgut induces an enhancement of triphenyl phosphate hydroxylation.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.2139/ssrn.4220639
Abstract: Fiber shedding from artificial textiles is among the primary sources of pervasive microplastics in various aquatic habitats. To avoid molten drop burning, triphenyl phosphate (TPhP), a typical flame retardant additive, is commonly incorporated into textile… read more here.
Keywords: microplastic fibers; high accumulation; triphenyl phosphate; fish hindgut ... See more keywords