The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
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DOI: 10.1126/scisignal.aah4273
Abstract: A small-molecule inhibitor of the kinase TPL2 shows efficacy in rodent models of inflammation. Targeting inflammatory neutrophils Neutrophils and monocytes are innate immune cells that establish an inflammatory response to infection. Because of their numbers,… read more here.
Keywords: kinase; inflammation; p38; tpl2 ... See more keywords