Thiopurine S-methyltransferase (TPMT) Activity Cutoffs in the Thai population.
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DOI: 10.1177/00045632251381058
Abstract: BACKGROUND Thiopurine S-methyltransferase (TPMT) is crucial for metabolising thiopurine drugs. This study aimed to establish the cutoff values for TPMT activity in a cohort of healthy individuals. We defined normal TPMT activity ranges and identified… read more here.
Keywords: cutoff values; tpmt activity; thiopurine; activity ... See more keywords
Genetic Variants of Pre-microRNAs A-499G(rs3746444) and T-196a2C(rs11614913) with Ulcerative Colitis (UC) and Investigated with Thiopurine-S-Methyltransferase (TPMT) Activity.
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DOI: 10.7754/clin.lab.2017.170502
Abstract: BACKGROUND Abnormal expression and different splicing of miRNAs are involved in several human inflammatory disorders. It has been suggested that gene variants of miRNAs may be associated with increased risk of ulcerative colitis (UC). We… read more here.
Keywords: 499g rs3746444; mirna 499g; tpmt; tpmt activity ... See more keywords