Articles with "tpn171" as a keyword



Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Patients With Mild or Moderate Hepatic Impairment Versus Participants With Normal Hepatic Function: A Phase 1 Study

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Published in 2025 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1535

Abstract: TPN171 is a phosphodiesterase‐5 inhibitor. It is currently being developed in China to treat pulmonary arterial hypertension and erectile dysfunction (ED). This study aimed to compare the pharmacokinetics and safety of TPN171 across participants with… read more here.

Keywords: mild moderate; participants normal; tpn171; study ... See more keywords