Articles with "tpo" as a keyword



High level of thyroid peroxidase antibodies as a detrimental risk of pregnancy outcomes in euthyroid women undergoing ART: A meta‐analysis

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Published in 2023 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.23677

Abstract: Thyroid autoimmunity (TAI) triggered by genetic and epigenetic variation occurs mostly in women of reproductive age. TAI is described mainly by positivity of anti‐thyroid peroxidase antibody (TPO‐Ab) and/or thyroglobulin antibody (TG‐Ab). TPO‐Ab, but not TG‐Ab,… read more here.

Keywords: meta analysis; tpo; risk; art ... See more keywords
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In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods

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Published in 2024 at "Archives of Toxicology"

DOI: 10.1007/s00204-024-03766-7

Abstract: Disruption of the thyroid hormone (TH) system is connected with diverse adverse health outcomes in wildlife and humans. It is crucial to develop and validate suitable in vitro assays capable of measuring the disruption of… read more here.

Keywords: thyroid peroxidase; inhibition; cell; thyroid ... See more keywords

Selective Aerobic Upgrading of Lignin-Derived Compound Using a Recyclable Dual-Functional TPO-Loaded Cu-BTC Catalyst

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Published in 2020 at "Waste and Biomass Valorization"

DOI: 10.1007/s12649-020-01009-1

Abstract: Abstract As oxidative conversion of lignin-derived compound, vanillic alcohol (VA), to vanillin aldehyde (VL) represents as a useful process for lignocellulosic biomass valorization. While catalytic aerobic oxidation by Cu and 2,2,6,6-tetramethylpiperidine 1-oxyl (TPO) with O… read more here.

Keywords: lignin derived; tpo; catalyst; derived compound ... See more keywords

The structure, function, and clinical use of the thrombopoietin receptor agonist avatrombopag.

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Published in 2021 at "Blood reviews"

DOI: 10.1016/j.blre.2021.100909

Abstract: Thrombopoietin regulates platelet production through activation of the thrombopoietin receptor (TPO-R). TPO-R agonists (TPO-RAs) are available to treat thrombocytopenia in chronic immune thrombocytopenia (ITP), chronic liver disease (CLD) patients who are undergoing a procedure, severe… read more here.

Keywords: thrombopoietin; avatrombopag; tpo; thrombopoietin receptor ... See more keywords

The encapsulation of intumescent flame retardants by poly-siloxane for thermoplastic polyolefin: Fire safety and water resistance

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Published in 2021 at "Polymer Degradation and Stability"

DOI: 10.1016/j.polymdegradstab.2021.109561

Abstract: Abstract The flammability of thermoplastic polyolefins (TPO) is a prior concern related to fire disasters. The fire safety strategy for TPO has not been settled because of serious waterproof property deteriorations caused by the presence… read more here.

Keywords: water; poly siloxane; flame retardant; fire safety ... See more keywords

Damp heat resilient thermoplastic polyolefin encapsulant for photovoltaic module encapsulation

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Published in 2021 at "Solar Energy Materials and Solar Cells"

DOI: 10.1016/j.solmat.2021.111024

Abstract: Abstract Thermoplastic polyolefin (TPO) is a non-crosslinking material used in photovoltaic module encapsulation. TPO thermal degradation and its weather stabilities are still not known. In this work, TPO laminates were prepared and subjected to extended… read more here.

Keywords: heat; photovoltaic module; damp heat; thermoplastic polyolefin ... See more keywords

Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease

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Published in 2024 at "Leukemia"

DOI: 10.1038/s41375-024-02219-5

Abstract: Thrombopoietin (Tpo), which binds to its specific receptor, the Mpl protein, is the major cytokine regulator of megakaryopoiesis and circulating platelet number. Tpo binding to Mpl triggers activation of Janus kinase 2 (Jak2) and phosphorylation… read more here.

Keywords: tyrosine residues; differential vivo; mpl y599; mpl ... See more keywords

Molecular insights on Eltrombopag: potential mitogen stimulants, angiogenesis, and therapeutic radioprotectant through TPO-R activation

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Published in 2024 at "Platelets"

DOI: 10.1080/09537104.2024.2359028

Abstract: Abstract The purpose of this study is to investigate the molecular interactions and potential therapeutic uses of Eltrombopag (EPAG), a small molecule that activates the cMPL receptor. EPAG has been found to be effective in… read more here.

Keywords: receptor; radiation; stem; activation ... See more keywords

P-680 Does thyroid autoimmunity impact fertility outcome in infertile women? An observational cohort study evaluating ART outcomes

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Published in 2025 at "Human Reproduction"

DOI: 10.1093/humrep/deaf097.986

Abstract: Does thyroid autoimmunity, i.e. thyroid peroxidase antibodies (TPO-Ab), influence ART outcomes and does ICSI result in higher pregnancy rates in women with TPO-Ab? TPO-Ab do not significantly affect pregnancy rates or ART outcomes. ICSI does… read more here.

Keywords: art outcomes; pregnancy; thyroid autoimmunity; art ... See more keywords

Mutation Spectrum in TPO Gene of Bangladeshi Patients with Thyroid Dyshormonogenesis and Analysis of the Effects of Different Mutations on the Structural Features and Functions of TPO Protein through In Silico Approach

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Published in 2019 at "BioMed Research International"

DOI: 10.1155/2019/9218903

Abstract: Although thyroid dyshormonogenesis (TDH) accounts for 10-20% of congenital hypothyroidism (CH), the molecular etiology of TDH is unknown in Bangladesh. Thyroid peroxidase (TPO) is most frequently associated with TDH and the present study investigated the… read more here.

Keywords: tpo; kcal mol; tpo protein; mol kcal ... See more keywords

Application of Temperature Programmed Oxidation-Infrared Technique in the Analysis of Sulfur Occurrence and Genesis in Phosphate Rock

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Published in 2022 at "Journal of Analytical Methods in Chemistry"

DOI: 10.1155/2022/3255760

Abstract: In this study, a temperature programmed oxidation-infrared (TPO-IR) technique was improved and applied in the analysis of sulfur occurrence and genesis in phosphate rock. Phosphate rocks from three regions (KYP, ZJP, and WAP) were selected… read more here.

Keywords: phosphate; tpo; sulfur; temperature ... See more keywords