Adenovirus vector encoding TPPII ignites HBVâspecific CTL response by activating autophagy in CD8+ T cell
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13638
Abstract: Early studies have shown that autophagy and TPPII are associated with HBV infection. In this study, adenovirus vector containing TPPII was constructed to immunize HBV transgenic mice in vivo to explore the potential mechanism of… read more here.
Keywords: microscopy; autophagy cd8; adenovirus vector; tppii ... See more keywords
Unveiling a novel serpinB2/tripeptidyl peptidase II signaling axis during senescence.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259513
Abstract: Tripeptidyl peptidase II (TPPII) degrades N-terminal tripeptides from proteins and peptides. Studies in both human and mice have shown that TPPII deficiency is linked to cellular immune-senescence, lifespan regulation, and the aging process. However, the… read more here.
Keywords: senescence; serpinb2; tripeptidyl peptidase; activity ... See more keywords