Topotecan reduces sepsis‐induced acute lung injury and decreases the inflammatory response via the inhibition of the NF‐κB signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12070
Abstract: Abstract This study aims to determine the function of topotecan (TPT) in acute lung injury (ALI) induced by sepsis. The mouse sepsis model was constructed through cecal ligation and puncture (CLP). The ALI score and… read more here.
Keywords: sepsis; acute lung; lung injury; lung ... See more keywords
Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer
Sign Up to like & getrecommendations! Published in 2024 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-023-04914-w
Abstract: Several commercially available triorganotin compounds were previously found to function as agonist ligands for nuclear retinoid X receptor (RXR) molecules. Triphenyltin isoselenocyanate (TPT-NCSe), a novel selenium atom containing a derivative of triorganotin origin, was found… read more here.
Keywords: cell lines; nuclear retinoid; tpt; retinoid receptor ... See more keywords
Effects of exposure to triphenyltin (TPT) contaminant on sperm activity in adulthood of Calomys laucha exposed through breastfeeding
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-04365-1
Abstract: Triphenyltin (TPT) is an organotin compound (OT), primarily used in agriculture and in the composition of antifouling paints for ships worldwide. Studies have showed its effects as an endocrine disrupter in several organisms by preventing… read more here.
Keywords: exposed breastfeeding; calomys laucha; tpt; effects exposure ... See more keywords
Toxicity of triphenyltin on the development of retinal axons in zebrafish at low dose.
Sign Up to like & getrecommendations! Published in 2017 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2017.05.009
Abstract: The impacts of triphenyltin (TPT) on ecological health are of particular concern due to the unexpectedly high levels found in wild fish around the world. Here, zebrafish embryos were exposed to TPT via in ovo… read more here.
Keywords: development retinal; low dose; tpt; toxicity ... See more keywords
Design, synthesis and photophysical investigation of triphenylamine-bithiophene dyes as RGB emitters for white light applications
Sign Up to like & getrecommendations! Published in 2018 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2018.06.001
Abstract: Abstract A set of three triphenylamine-bithiophene based Donor-Acceptor (D-A) molecules viz. TPT, TPT-Ben and TPT-Ac were designed, synthesized and studied for their photophysical properties. Systematic density functional theory (DFT) calculations have been performed on the… read more here.
Keywords: design synthesis; tpt; synthesis photophysical; photophysical investigation ... See more keywords
Modulatory effect of fructooligosaccharide against triphenyltin-induced oxidative stress and immune suppression in goldfish (Carassius auratus).
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.111966
Abstract: Triphenyltin (TPT) is a widely used pesticide that is highly toxic to a variety of organisms, including humans, and is a potential contributor to environmental pollution. The present study was conducted to evaluate the oxidative… read more here.
Keywords: tpt; induced oxidative; group; tpt induced ... See more keywords
Effects of triphenyltin on glycinergic transmission on rat spinal neurons
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Research"
DOI: 10.1016/j.envres.2018.02.005
Abstract: &NA; Glycine is a fast inhibitory transmitter like &ggr;‐aminobutyric acid in the mammalian spinal cord and brainstem, and it is involved in motor reflex, nociception, and neuronal development. Triphenyltin (TPT) is an organometallic compound causing… read more here.
Keywords: spinal neurons; glycinergic transmission; tpt; wild creatures ... See more keywords
Prehospital paramedic pleural decompression: A systematic review.
Sign Up to like & getrecommendations! Published in 2021 at "Injury"
DOI: 10.1016/j.injury.2021.08.008
Abstract: BACKGROUND Tension pneumothorax (TPT) is a frequent life-threat following thoracic injury. Time-critical decompression of the pleural cavity improves survival. However, whilst paramedics utilise needle thoracostomy (NT) and/or finger thoracostomy (FT) in the prehospital setting, the… read more here.
Keywords: paramedic pleural; decompression; pleural decompression; tpt ... See more keywords
C60 Fullerene Clusters Stabilize the Biologically Inactive Form of Topotecan.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00071
Abstract: There is a range of experimental proofs that biologically relevant compounds change their activity in the presence of C60 fullerene clusters in aqueous solution, which most frequently act as a nanoplatform for drug delivery. Inspired… read more here.
Keywords: c60 fullerene; fullerene; fullerene clusters; tpt ... See more keywords
Designing a Polyoxometalate-Incorporated Metal-Organic Framework for Reduction of Nitroarenes to Anilines by Sequential Proton-Coupled Electron Transfers.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c00106
Abstract: Developing new photocatalysts for reduction of nitroarenes to anilines under mild conditions is very significant. Herein, a new polyoxometalate-based metal-organic framework (POMOF), {[Co(H2O)]2[Co2(H2O)6(TPT)][Co(TPT)PW11O39]}·3H2O·TPT (namely, CoW-TPT, TPT = 2,4,6-tri(4-pyridyl)-1,3,5-triazine), was prepared by incorporating Co(II)-substituted Keggin-type anions… read more here.
Keywords: framework; tpt; electron; nitroarenes anilines ... See more keywords
Three dimensional printed degradable and conductive polymer scaffolds promote chondrogenic differentiation of chondroprogenitor cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm00621a
Abstract: Conductive polymers have been used for various biomedical applications including biosensors, tissue engineering and regenerative medicine. However, the poor processability and brittleness of these polymers hinder the fabrication of three-dimensional structures with desirable geometries. Moreover,… read more here.
Keywords: three dimensional; medicine; differentiation chondroprogenitor; tpt ... See more keywords