Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension.
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DOI: 10.1165/rcmb.2024-0365oc
Abstract: Inhaled pharmacotherapies are promising treatment options for patients with pulmonary arterial hypertension (PAH) as they minimize extrapulmonary adverse effects. Recently, we developed a highly specific inhibitor (TPHi) of the serotonin synthesizing enzyme tryptophan hydroxylase 1,… read more here.
Keywords: arterial hypertension; inhalation; tpt 004; inhibitor ... See more keywords