Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery
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DOI: 10.1155/2021/9968602
Abstract: Background Chemotherapeutic drugs cause severe toxicities if administered unprotected, without proper targeting, and controlled release. In this study, we developed topotecan- (TPT-) loaded solid lipid nanoparticles (SLNs) for their chemotherapeutic effect against colorectal cancer. The… read more here.
Keywords: tpt slns; thermoresponsive hydrogel; hydrogel system; tpt ... See more keywords