Photo from wikipedia
Sign Up to like & get
recommendations!
1
Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5683
Abstract: Ovarian cancer (OC) is one of the fatal gynecologic malignancies. However, there are no effective prognostic or therapeutic indicators for OC. Herein, we aim to reveal the potential function of targeting protein for Xklp2 (TPX2)…
read more here.
Keywords:
ovarian tumorigenesis;
tumorigenesis interacting;
promotes ovarian;
tpx2 promotes ... See more keywords
Photo by nci from unsplash
Sign Up to like & get
recommendations!
1
Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.164
Abstract: Targeting protein for Xenopus kinesin-like protein 2 (TPX2) is a microtubule-associated protein required for mitosis and spindle assembly. Previous studies showed that TPX2 is overexpressed in various human cancers and promotes cancer progression. In this…
read more here.
Keywords:
pi3k akt;
breast cancer;
signaling pathway;
tpx2 ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-019-14087-0
Abstract: Phase separation of substrates and effectors is proposed to enhance biological reaction rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching microtubule nucleation in spindles and functions with the substrate tubulin…
read more here.
Keywords:
microtubule nucleation;
phase separation;
tpx2;
Sign Up to like & get
recommendations!
0
Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2019172
Abstract: ABSTRACT Circular RNAs (circRNAs) have shown pivotal regulatory roles in tumorigenesis and progression. Our purpose was to analyze the role of circRNA La ribonucleoprotein 1B (circ-LARP1B; hsa_circ_0070934) in cutaneous squamous cell carcinoma (CSCC) progression and…
read more here.
Keywords:
circ;
circ larp1b;
tpx2;
mir 515 ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-06-0476
Abstract: Temporal and spatial regulation of mitotic motor proteins is required for proper spindle assembly and function. A single microtubule-associated protein, TPX2, regulates both kinesin-5 and kinesin-12 family members to support bipolar spindle formation and maintenance.
read more here.
Keywords:
microtubule;
regulation kif15;
tpx2;
kif15 localization ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
1
Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6085948
Abstract: The activation of the androgen receptor (AR) pathway is crucial in the progression of human prostate cancer. Results of the present study indicated that the target protein xenopus kinesin-like protein (TPX2) enhanced the transcription activation…
read more here.
Keywords:
proliferation;
prostate;
androgen receptor;
tpx2 ... See more keywords
Photo by nci from unsplash
Sign Up to like & get
recommendations!
0
Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.25870.1
Abstract: Background: FAM161A is a microtubule-associated protein conserved widely across eukaryotes, which is mutated in the inherited blinding disease Retinitis Pigmentosa-28. FAM161A is also a centrosomal protein, being a core component of a complex that forms…
read more here.
Keywords:
protein;
microtubule;
fam161a;
retinitis pigmentosa ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2019 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2019.4371
Abstract: Hepatocellular carcinoma (HCC) is one of the primary causes of cancer-associated deaths worldwide. Current treatment methods include surgical resection, chemotherapy and radiotherapy; however the curative rate remains low, thus novel treatments are required. The aim…
read more here.
Keywords:
protein;
tpx2 silencing;
signaling pathway;
tpx2 ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.8810
Abstract: Ovarian cancer, with its high morbidity, has one of the highest mortality rates among gynecological malignant tumors. Overexpression of targeting protein for Xklp2 (TPX2) has been identified in numerous malignant tumors. The present study sought…
read more here.
Keywords:
skov3;
microvesicles ultrasonic;
tpx2;
ultrasonic radiation ... See more keywords
Photo by nci from unsplash
Sign Up to like & get
recommendations!
0
Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13256
Abstract: Targeting protein for Xenopus kinesin-like protein 2 (TPX2) is upregulated in various tumors, and several studies have demonstrated the role of TPX2 as a prognostic marker in cancer. However, the function of TPX2 in neuroblastoma…
read more here.
Keywords:
cell;
role;
prognostic marker;
tpx2 prognostic ... See more keywords